EXPERIENCE OF TREATMENT WITH RITUXIMAB IN PATIENT WITH JUVENILE POLYARTERITIS
<em>The article presents a case report of severe course of nodular polyarteritis. The disease was highly active, aggressive, and refractory to treatment with corticosteroids and cyclophosphamide combined with plasmapheresis and drugs for microcirculation improvement. The treatment with chimeri...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2011-01-01
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| Series: | Вопросы современной педиатрии |
| Online Access: | http://vsp.spr-journal.ru:80/jour/article/view/912 |
| _version_ | 1797718775075700736 |
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| author | E.I. Alexeeva T.V. Sleptsova S.I. Valieva T.M. Bzarova K.B. Isaeva R.V. Denisova E.V. Mitenko |
| author_facet | E.I. Alexeeva T.V. Sleptsova S.I. Valieva T.M. Bzarova K.B. Isaeva R.V. Denisova E.V. Mitenko |
| author_sort | E.I. Alexeeva |
| collection | DOAJ |
| description | <em>The article presents a case report of severe course of nodular polyarteritis. The disease was highly active, aggressive, and refractory to treatment with corticosteroids and cyclophosphamide combined with plasmapheresis and drugs for microcirculation improvement. The treatment with chimerical anti-CD20 monoclonal antibodies — rituximab — was successful. Symptoms of intoxication and tromboangiatic syndrome decreased in 4 weeks. Disease was stopped up to 16th week. The case report demonstrates high efficacy of rituximab: patient with severe nodular polyarteritis remains clinical and laboratory remission during 52 weeks.</em><br /><strong><em>Key words: children, nodular polyarteritis, rituximab.</em></strong><br /><span style="text-decoration: underline;"><em><em>(Voprosy sovremennoi pediatrii — Current Pediatrics. </em></em><em><em>2011; 10 (2): 193–200)</em></em></span> |
| first_indexed | 2024-03-12T08:55:18Z |
| format | Article |
| id | doaj.art-e1e14ee09f7e4a0abded384f74cc3848 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T08:55:18Z |
| publishDate | 2011-01-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-e1e14ee09f7e4a0abded384f74cc38482023-09-02T16:08:12Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352011-01-01102193200913EXPERIENCE OF TREATMENT WITH RITUXIMAB IN PATIENT WITH JUVENILE POLYARTERITISE.I. Alexeeva0T.V. Sleptsova1S.I. Valieva2T.M. Bzarova3K.B. Isaeva4R.V. Denisova5E.V. Mitenko6Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow I.M. Sechenov First Moscow State Medical UniversityScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow<em>The article presents a case report of severe course of nodular polyarteritis. The disease was highly active, aggressive, and refractory to treatment with corticosteroids and cyclophosphamide combined with plasmapheresis and drugs for microcirculation improvement. The treatment with chimerical anti-CD20 monoclonal antibodies — rituximab — was successful. Symptoms of intoxication and tromboangiatic syndrome decreased in 4 weeks. Disease was stopped up to 16th week. The case report demonstrates high efficacy of rituximab: patient with severe nodular polyarteritis remains clinical and laboratory remission during 52 weeks.</em><br /><strong><em>Key words: children, nodular polyarteritis, rituximab.</em></strong><br /><span style="text-decoration: underline;"><em><em>(Voprosy sovremennoi pediatrii — Current Pediatrics. </em></em><em><em>2011; 10 (2): 193–200)</em></em></span>http://vsp.spr-journal.ru:80/jour/article/view/912 |
| spellingShingle | E.I. Alexeeva T.V. Sleptsova S.I. Valieva T.M. Bzarova K.B. Isaeva R.V. Denisova E.V. Mitenko EXPERIENCE OF TREATMENT WITH RITUXIMAB IN PATIENT WITH JUVENILE POLYARTERITIS Вопросы современной педиатрии |
| title | EXPERIENCE OF TREATMENT WITH RITUXIMAB IN PATIENT WITH JUVENILE POLYARTERITIS |
| title_full | EXPERIENCE OF TREATMENT WITH RITUXIMAB IN PATIENT WITH JUVENILE POLYARTERITIS |
| title_fullStr | EXPERIENCE OF TREATMENT WITH RITUXIMAB IN PATIENT WITH JUVENILE POLYARTERITIS |
| title_full_unstemmed | EXPERIENCE OF TREATMENT WITH RITUXIMAB IN PATIENT WITH JUVENILE POLYARTERITIS |
| title_short | EXPERIENCE OF TREATMENT WITH RITUXIMAB IN PATIENT WITH JUVENILE POLYARTERITIS |
| title_sort | experience of treatment with rituximab in patient with juvenile polyarteritis |
| url | http://vsp.spr-journal.ru:80/jour/article/view/912 |
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