Effect of Expression of Human Glucosylceramidase 2 Isoforms on Lipid Profiles in COS-7 Cells
Glucosylceramide (GlcCer) is a major membrane lipid and the precursor of gangliosides. GlcCer is mainly degraded by two enzymes, lysosomal acid β-glucosidase (GBA) and nonlysosomal β-glucosidase (GBA2), which may have different isoforms because of alternative splicing. To understand which GBA2 isofo...
Main Authors: | Peeranat Jatooratthawichot, Chutima Talabnin, Lukana Ngiwsara, Yepy Hardi Rustam, Jisnuson Svasti, Gavin E. Reid, James R. Ketudat Cairns |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
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Series: | Metabolites |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-1989/10/12/488 |
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