Retinal findings in membranoproliferative glomerulonephritis
Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed for a period of 1.5–37 years. Four patients (...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-09-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993616302821 |
| _version_ | 1811315010221113344 |
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| author | Ahmad M. Mansour Luiz H. Lima J. Fernando Arevalo Miguel Hage Amaro Virginia Lozano Alaa Bou Ghannam Errol W. Chan |
| author_facet | Ahmad M. Mansour Luiz H. Lima J. Fernando Arevalo Miguel Hage Amaro Virginia Lozano Alaa Bou Ghannam Errol W. Chan |
| author_sort | Ahmad M. Mansour |
| collection | DOAJ |
| description | Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography.
Observations: Three women and one man were followed for a period of 1.5–37 years. Four patients (8 eyes) had drusen detected at first fundus exam at age 24, 29, 50 and 55. Three patients (6 eyes) had diffuse thickening of Bruch's membrane, and two patients (3 eyes) had detachment of the retinal pigment epithelium with serous retinal detachment. Drusen tended to widen over a period of 10-year follow-up in one case.
Conclusions and importance: Drusen remain the ocular stigmata for MPGN occuring at an early age. The retinal disease is progressive with gradual thickening of Bruch's membrane and occurrence of retinal pigment epithelium detachment. |
| first_indexed | 2024-04-13T11:22:38Z |
| format | Article |
| id | doaj.art-e1e6783a62e44ad1b85a6415f642e03c |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-04-13T11:22:38Z |
| publishDate | 2017-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-e1e6783a62e44ad1b85a6415f642e03c2022-12-22T02:48:47ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362017-09-017C839010.1016/j.ajoc.2017.06.011Retinal findings in membranoproliferative glomerulonephritisAhmad M. Mansour0Luiz H. Lima1J. Fernando Arevalo2Miguel Hage Amaro3Virginia Lozano4Alaa Bou Ghannam5Errol W. Chan6Department of Ophthalmology, American University of Beirut, Beirut, LebanonDepartment of Ophthalmology and Visual Sciences, Federal University of Sao Paulo, Sao Paulo, BrazilWilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAInstituto de Olhos e Laser de Belém, Federal University of Sao Paulo, Sao Paulo, BrazilDepartment of Ophthalmology, Complejo Hospitalario Universitario de Canarias, Tenerife, Canary Islands, SpainDepartment of Ophthalmology, American University of Beirut, Beirut, LebanonDepartment of Ophthalmology, McGill University, Montreal, CanadaPurpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed for a period of 1.5–37 years. Four patients (8 eyes) had drusen detected at first fundus exam at age 24, 29, 50 and 55. Three patients (6 eyes) had diffuse thickening of Bruch's membrane, and two patients (3 eyes) had detachment of the retinal pigment epithelium with serous retinal detachment. Drusen tended to widen over a period of 10-year follow-up in one case. Conclusions and importance: Drusen remain the ocular stigmata for MPGN occuring at an early age. The retinal disease is progressive with gradual thickening of Bruch's membrane and occurrence of retinal pigment epithelium detachment.http://www.sciencedirect.com/science/article/pii/S2451993616302821DrusenMacular degenerationMembranoproliferative glomerulonephritisRetinal pigment epithelial detachment |
| spellingShingle | Ahmad M. Mansour Luiz H. Lima J. Fernando Arevalo Miguel Hage Amaro Virginia Lozano Alaa Bou Ghannam Errol W. Chan Retinal findings in membranoproliferative glomerulonephritis American Journal of Ophthalmology Case Reports Drusen Macular degeneration Membranoproliferative glomerulonephritis Retinal pigment epithelial detachment |
| title | Retinal findings in membranoproliferative glomerulonephritis |
| title_full | Retinal findings in membranoproliferative glomerulonephritis |
| title_fullStr | Retinal findings in membranoproliferative glomerulonephritis |
| title_full_unstemmed | Retinal findings in membranoproliferative glomerulonephritis |
| title_short | Retinal findings in membranoproliferative glomerulonephritis |
| title_sort | retinal findings in membranoproliferative glomerulonephritis |
| topic | Drusen Macular degeneration Membranoproliferative glomerulonephritis Retinal pigment epithelial detachment |
| url | http://www.sciencedirect.com/science/article/pii/S2451993616302821 |
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