Immune Thymic Profile of the MOG-Induced Experimental Autoimmune Encephalomyelitis Mouse Model

Immune Thymic Profile of the MOG-Induced Experimental Autoimmune Encephalomyelitis Mouse Model

Multiple sclerosis (MS) is a chronic, immune-mediated, demyelinating disease that affects the neurons of the central nervous system. Activated T cells, specific for myelin epitopes, cross the brain barriers, and react against the myelin sheath, leading to demyelination. Since T cells are generated w...

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Bibliographic Details
Main Authors: Sofia P. das Neves, Cláudia Serre-Miranda, Claudia Nobrega, Susana Roque, João J. Cerqueira, Margarida Correia-Neves, Fernanda Marques
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
autoimmunity
multiple sclerosis
rodent
experimental autoimmune encephalomyelitis
thymus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02335/full

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