Is there a role for e-cigarettes in smoking cessation?

The use of e-cigarettes has dramatically increased over the past few years and their role in smoking cessation remains controversial. Several clinical studies have evaluated their efficacy in smoking cessation but most of them are prospective cohort studies. Only two randomized, controlled trials ha...

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Main Authors: Charlotte Leduc, Elisabeth Quoix
Format: Article
Language:English
Published: SAGE Publishing 2016-04-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/1753465815621233
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author Charlotte Leduc
Elisabeth Quoix
author_facet Charlotte Leduc
Elisabeth Quoix
author_sort Charlotte Leduc
collection DOAJ
description The use of e-cigarettes has dramatically increased over the past few years and their role in smoking cessation remains controversial. Several clinical studies have evaluated their efficacy in smoking cessation but most of them are prospective cohort studies. Only two randomized, controlled trials have compared e-cigarettes versus placebo or patches. A meta-analysis of these two randomized, controlled trials has been performed. Nicotine-containing e-cigarettes appear to help smokers unable to stop smoking altogether to reduce their cigarette consumption when compared with placebo. However, these results are rated ‘low’ by GRADE standards. Many cohort studies have been conducted, with contradictory results. For some, e-cigarettes could increase the risk of nonsmokers developing nicotine dependence and of current smokers maintaining their dependence. The debate remains open and more randomized trials are needed with long-term data about the efficacy and safety of e-cigarettes.
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spelling doaj.art-e1eff796b6ee458ab606647c042f73172022-12-22T00:40:05ZengSAGE PublishingTherapeutic Advances in Respiratory Disease1753-46581753-46662016-04-011010.1177/1753465815621233Is there a role for e-cigarettes in smoking cessation?Charlotte LeducElisabeth QuoixThe use of e-cigarettes has dramatically increased over the past few years and their role in smoking cessation remains controversial. Several clinical studies have evaluated their efficacy in smoking cessation but most of them are prospective cohort studies. Only two randomized, controlled trials have compared e-cigarettes versus placebo or patches. A meta-analysis of these two randomized, controlled trials has been performed. Nicotine-containing e-cigarettes appear to help smokers unable to stop smoking altogether to reduce their cigarette consumption when compared with placebo. However, these results are rated ‘low’ by GRADE standards. Many cohort studies have been conducted, with contradictory results. For some, e-cigarettes could increase the risk of nonsmokers developing nicotine dependence and of current smokers maintaining their dependence. The debate remains open and more randomized trials are needed with long-term data about the efficacy and safety of e-cigarettes.https://doi.org/10.1177/1753465815621233
spellingShingle Charlotte Leduc
Elisabeth Quoix
Is there a role for e-cigarettes in smoking cessation?
Therapeutic Advances in Respiratory Disease
title Is there a role for e-cigarettes in smoking cessation?
title_full Is there a role for e-cigarettes in smoking cessation?
title_fullStr Is there a role for e-cigarettes in smoking cessation?
title_full_unstemmed Is there a role for e-cigarettes in smoking cessation?
title_short Is there a role for e-cigarettes in smoking cessation?
title_sort is there a role for e cigarettes in smoking cessation
url https://doi.org/10.1177/1753465815621233
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