Elevated osteopontin and IFNy serum levels and increased neutrophil-to-lymphocyte ratio are associated with the severity of symptoms in schizophrenia

Elevated osteopontin and IFNy serum levels and increased neutrophil-to-lymphocyte ratio are associated with the severity of symptoms in schizophrenia

Introduction Inflammation and immune dysregulation could contribute to the pathogenesis of schizophrenia. Osteopontin (OPN) is a key cytokine-like molecule in cellular immune response and it can directly modulate the cytokine expression and survival of microglia. Furthermore, its mRNA expression is...

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Bibliographic Details
Main Authors: M. Kovács, T. Tényi, R. Kugyelka, L. Prenek, R. Herold, P. Balogh, D. Simon
Format: Article
Language:English
Published: Cambridge University Press 2022-06-01
Series:European Psychiatry
Subjects:
osteopontin
Cytokines
inflammation
schizophrénia
Online Access:https://www.cambridge.org/core/product/identifier/S0924933822003029/type/journal_article

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