Colonic transit time and pressure based on Bernoulli’s principle
Yoshiharu Uno Office Uno Column, Yota, Onoe-Cho, Kakogawa, Japan Purpose: Variations in the caliber of human large intestinal tract causes changes in pressure and the velocity of its contents, depending on flow volume, gravity, and density, which are all variables of Bernoulli’s principle....
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2018-04-01
|
| Series: | Clinical and Experimental Gastroenterology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/colonic-transit-time-and-pressure-based-on-bernoullis-principle-peer-reviewed-article-CEG |
| _version_ | 1818944591896772608 |
|---|---|
| author | Uno Y |
| author_facet | Uno Y |
| author_sort | Uno Y |
| collection | DOAJ |
| description | Yoshiharu Uno Office Uno Column, Yota, Onoe-Cho, Kakogawa, Japan Purpose: Variations in the caliber of human large intestinal tract causes changes in pressure and the velocity of its contents, depending on flow volume, gravity, and density, which are all variables of Bernoulli’s principle. Therefore, it was hypothesized that constipation and diarrhea can occur due to changes in the colonic transit time (CTT), according to Bernoulli’s principle. In addition, it was hypothesized that high amplitude peristaltic contractions (HAPC), which are considered to be involved in defecation in healthy subjects, occur because of cecum pressure based on Bernoulli’s principle.Methods: A virtual healthy model (VHM), a virtual constipation model and a virtual diarrhea model were set up. For each model, the CTT was decided according to the length of each part of the colon, and then calculating the velocity due to the cecum inflow volume. In the VHM, the pressure change was calculated, then its consistency with HAPC was verified.Results: The CTT changed according to the difference between the cecum inflow volume and the caliber of the intestinal tract, and was inversely proportional to the cecum inflow volume. Compared with VHM, the CTT was prolonged in the virtual constipation model, and shortened in the virtual diarrhea model. The calculated pressure of the VHM and the gradient of the interlocked graph were similar to that of HAPC.Conclusion: The CTT and HAPC can be explained by Bernoulli’s principle, and constipation and diarrhea may be fundamentally influenced by flow dynamics. Keywords: colonic transit time, Bernoulli’s principle, constipation, diarrhea, high amplitude peristaltic contractions |
| first_indexed | 2024-12-20T07:45:40Z |
| format | Article |
| id | doaj.art-e1f8dd14722c472aa3ad1945190d5163 |
| institution | Directory Open Access Journal |
| issn | 1178-7023 |
| language | English |
| last_indexed | 2024-12-20T07:45:40Z |
| publishDate | 2018-04-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical and Experimental Gastroenterology |
| spelling | doaj.art-e1f8dd14722c472aa3ad1945190d51632022-12-21T19:48:00ZengDove Medical PressClinical and Experimental Gastroenterology1178-70232018-04-01Volume 1115316337591Colonic transit time and pressure based on Bernoulli’s principleUno YYoshiharu Uno Office Uno Column, Yota, Onoe-Cho, Kakogawa, Japan Purpose: Variations in the caliber of human large intestinal tract causes changes in pressure and the velocity of its contents, depending on flow volume, gravity, and density, which are all variables of Bernoulli’s principle. Therefore, it was hypothesized that constipation and diarrhea can occur due to changes in the colonic transit time (CTT), according to Bernoulli’s principle. In addition, it was hypothesized that high amplitude peristaltic contractions (HAPC), which are considered to be involved in defecation in healthy subjects, occur because of cecum pressure based on Bernoulli’s principle.Methods: A virtual healthy model (VHM), a virtual constipation model and a virtual diarrhea model were set up. For each model, the CTT was decided according to the length of each part of the colon, and then calculating the velocity due to the cecum inflow volume. In the VHM, the pressure change was calculated, then its consistency with HAPC was verified.Results: The CTT changed according to the difference between the cecum inflow volume and the caliber of the intestinal tract, and was inversely proportional to the cecum inflow volume. Compared with VHM, the CTT was prolonged in the virtual constipation model, and shortened in the virtual diarrhea model. The calculated pressure of the VHM and the gradient of the interlocked graph were similar to that of HAPC.Conclusion: The CTT and HAPC can be explained by Bernoulli’s principle, and constipation and diarrhea may be fundamentally influenced by flow dynamics. Keywords: colonic transit time, Bernoulli’s principle, constipation, diarrhea, high amplitude peristaltic contractions https://www.dovepress.com/colonic-transit-time-and-pressure-based-on-bernoullis-principle-peer-reviewed-article-CEGcolonic transit timeBernoulli's Principleconstipationdiarrheahigh amplitude peristaltic contractions |
| spellingShingle | Uno Y Colonic transit time and pressure based on Bernoulli’s principle Clinical and Experimental Gastroenterology colonic transit time Bernoulli's Principle constipation diarrhea high amplitude peristaltic contractions |
| title | Colonic transit time and pressure based on Bernoulli’s principle |
| title_full | Colonic transit time and pressure based on Bernoulli’s principle |
| title_fullStr | Colonic transit time and pressure based on Bernoulli’s principle |
| title_full_unstemmed | Colonic transit time and pressure based on Bernoulli’s principle |
| title_short | Colonic transit time and pressure based on Bernoulli’s principle |
| title_sort | colonic transit time and pressure based on bernoulli rsquo s principle |
| topic | colonic transit time Bernoulli's Principle constipation diarrhea high amplitude peristaltic contractions |
| url | https://www.dovepress.com/colonic-transit-time-and-pressure-based-on-bernoullis-principle-peer-reviewed-article-CEG |
| work_keys_str_mv | AT unoy colonictransittimeandpressurebasedonbernoullirsquosprinciple |