Defibrotide improved the outcome of monocrotaline induced rat hepatic sinusoidal obstruction syndrome

Abstract Background and aim Pyrrolizidine alkaloids (PA) induced hepatic sinusoidal obstruction syndrome (HSOS) occurred worldwide and the mortality rate remained high because there were no specific therapies. Defibrotide was effective for HSOS following hematopoietic stem cell transplantation. But...

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Détails bibliographiques
Auteurs principaux: Zhenli Liu, Shan Liang, Xinhuan Wei, Xiaofei Du, Jing Zhang
Format: Article
Langue:English
Publié: BMC 2022-12-01
Collection:BMC Gastroenterology
Sujets:
Accès en ligne:https://doi.org/10.1186/s12876-022-02523-3