Protective Effects of Glucose-Related Protein 78 and 94 on Cisplatin-Mediated Ototoxicity

Protective Effects of Glucose-Related Protein 78 and 94 on Cisplatin-Mediated Ototoxicity

Cisplatin is a widely used chemotherapeutic drug for treating various solid tumors. Ototoxicity is a major dose-limiting side effect of cisplatin, which causes progressive and irreversible sensorineural hearing loss. Here, we examined the protective effects of glucose-related protein (GRP) 78 and 94...

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Bibliographic Details
Main Authors: Junyeong Yi, Tae Su Kim, Jhang Ho Pak, Jong Woo Chung
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
cisplatin
ototoxicity
mild ER stress condition
GRP78
GRP94
auditory cells
Online Access:https://www.mdpi.com/2076-3921/9/8/686

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