Medical cannabis for treatment-resistant combat PTSD
Targeting the endocannabinoid system may have a role in the treatment of post-traumatic stress disorder (PTSD). However, few studies have examined the effectiveness of cannabis on symptoms of PTSD, and more research is needed to ascertain cannabis’ effectiveness. In this retrospective naturalistic s...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1014630/full |
| _version_ | 1828059172366712832 |
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| author | Nitsa Nacasch Chen Avni Paz Toren Paz Toren |
| author_facet | Nitsa Nacasch Chen Avni Paz Toren Paz Toren |
| author_sort | Nitsa Nacasch |
| collection | DOAJ |
| description | Targeting the endocannabinoid system may have a role in the treatment of post-traumatic stress disorder (PTSD). However, few studies have examined the effectiveness of cannabis on symptoms of PTSD, and more research is needed to ascertain cannabis’ effectiveness. In this retrospective naturalistic study, we followed 14 relatively mature (32-68 years of age), treatment-resistant, chronic combat post-traumatic patients who remained severely symptomatic despite treatment with many lines of conventional treatment prior to receiving medicinal cannabis. Our findings show that total sleep score, subjective sleep quality, and sleep duration significantly improved (p < 0.01). Total PTSD symptom score and its subdomains (intrusiveness, avoidance, and alertness) showed improvement (p < 0.05). However, there was no improvement in the frequency of nightmares (p = 0.27). The mean follow-up time was 1.1 ± 0.8 years (range of 0.5 to 3 years). |
| first_indexed | 2024-04-10T21:38:36Z |
| format | Article |
| id | doaj.art-e1ff89fee95c4f9fa4f32509ec2edd64 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-10T21:38:36Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-e1ff89fee95c4f9fa4f32509ec2edd642023-01-19T07:49:50ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-01-011310.3389/fpsyt.2022.10146301014630Medical cannabis for treatment-resistant combat PTSDNitsa Nacasch0Chen Avni1Paz Toren2Paz Toren3Clalit Health Services Community Division, Ramat-Chen Brull Mental Health Center, Tel Aviv-Yafo, IsraelClalit Health Services Community Division, Ramat-Chen Brull Mental Health Center, Tel Aviv-Yafo, IsraelClalit Health Services Community Division, Ramat-Chen Brull Mental Health Center, Tel Aviv-Yafo, IsraelSackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, IsraelTargeting the endocannabinoid system may have a role in the treatment of post-traumatic stress disorder (PTSD). However, few studies have examined the effectiveness of cannabis on symptoms of PTSD, and more research is needed to ascertain cannabis’ effectiveness. In this retrospective naturalistic study, we followed 14 relatively mature (32-68 years of age), treatment-resistant, chronic combat post-traumatic patients who remained severely symptomatic despite treatment with many lines of conventional treatment prior to receiving medicinal cannabis. Our findings show that total sleep score, subjective sleep quality, and sleep duration significantly improved (p < 0.01). Total PTSD symptom score and its subdomains (intrusiveness, avoidance, and alertness) showed improvement (p < 0.05). However, there was no improvement in the frequency of nightmares (p = 0.27). The mean follow-up time was 1.1 ± 0.8 years (range of 0.5 to 3 years).https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1014630/fullcannabispost-traumatic stress disorder (PTSD)treatment-resistantcombat PTSDposttraumatic diagnostic scale (PDS)pittsburgh sleep quality index (PSQI) |
| spellingShingle | Nitsa Nacasch Chen Avni Paz Toren Paz Toren Medical cannabis for treatment-resistant combat PTSD Frontiers in Psychiatry cannabis post-traumatic stress disorder (PTSD) treatment-resistant combat PTSD posttraumatic diagnostic scale (PDS) pittsburgh sleep quality index (PSQI) |
| title | Medical cannabis for treatment-resistant combat PTSD |
| title_full | Medical cannabis for treatment-resistant combat PTSD |
| title_fullStr | Medical cannabis for treatment-resistant combat PTSD |
| title_full_unstemmed | Medical cannabis for treatment-resistant combat PTSD |
| title_short | Medical cannabis for treatment-resistant combat PTSD |
| title_sort | medical cannabis for treatment resistant combat ptsd |
| topic | cannabis post-traumatic stress disorder (PTSD) treatment-resistant combat PTSD posttraumatic diagnostic scale (PDS) pittsburgh sleep quality index (PSQI) |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1014630/full |
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