Changes in immunocompetent guinea pigs immunizing with Francisella Tularensislipopoly-saccharide
Influence of Francisella tularensis lipopolysaccharide preparations on morphological changes in immunocompetent experimental animals was studied by subcutaneous introduction using survey microscopy and morphometric methods. Low expressed activation of B- and T-dependent bands in immunocompetent orga...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2013-11-01
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Series: | Acta Biomedica Scientifica |
Subjects: | |
Online Access: | https://www.actabiomedica.ru/jour/article/view/1693 |
Summary: | Influence of Francisella tularensis lipopolysaccharide preparations on morphological changes in immunocompetent experimental animals was studied by subcutaneous introduction using survey microscopy and morphometric methods. Low expressed activation of B- and T-dependent bands in immunocompetent organs was determined. Proliferation of antigen-presented cells at early stages of investigation indicates the cell immunity activation. Pathomorphological alterations caused by lipopolysaccharide inoculation are homogeneous and benignant. |
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ISSN: | 2541-9420 2587-9596 |