Changes in immunocompetent guinea pigs immunizing with Francisella Tularensislipopoly-saccharide
Influence of Francisella tularensis lipopolysaccharide preparations on morphological changes in immunocompetent experimental animals was studied by subcutaneous introduction using survey microscopy and morphometric methods. Low expressed activation of B- and T-dependent bands in immunocompetent orga...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2013-11-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/1693 |
| _version_ | 1797237515149639680 |
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| author | S. A. Vityazeva T. P. Starovoytova V. I. Dubrovina A. S. Sorokoumova V. V. Voitkova V. B. Nikolaev S. A. Tatarnikov K. M. Korytov |
| author_facet | S. A. Vityazeva T. P. Starovoytova V. I. Dubrovina A. S. Sorokoumova V. V. Voitkova V. B. Nikolaev S. A. Tatarnikov K. M. Korytov |
| author_sort | S. A. Vityazeva |
| collection | DOAJ |
| description | Influence of Francisella tularensis lipopolysaccharide preparations on morphological changes in immunocompetent experimental animals was studied by subcutaneous introduction using survey microscopy and morphometric methods. Low expressed activation of B- and T-dependent bands in immunocompetent organs was determined. Proliferation of antigen-presented cells at early stages of investigation indicates the cell immunity activation. Pathomorphological alterations caused by lipopolysaccharide inoculation are homogeneous and benignant. |
| first_indexed | 2024-03-08T12:20:23Z |
| format | Article |
| id | doaj.art-e205baba5fca4bbe99213a7a4972bcfa |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:20:58Z |
| publishDate | 2013-11-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-e205baba5fca4bbe99213a7a4972bcfa2024-03-28T07:49:12ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962013-11-01061271311639Changes in immunocompetent guinea pigs immunizing with Francisella Tularensislipopoly-saccharideS. A. Vityazeva0T. P. Starovoytova1V. I. Dubrovina2A. S. Sorokoumova3V. V. Voitkova4V. B. Nikolaev5S. A. Tatarnikov6K. M. Korytov7Irkutsk Antiplague Research Institute of RospotrebnadzorIrkutsk Antiplague Research Institute of RospotrebnadzorIrkutsk Antiplague Research Institute of RospotrebnadzorIrkutsk Antiplague Research Institute of RospotrebnadzorIrkutsk Antiplague Research Institute of RospotrebnadzorIrkutsk Antiplague Research Institute of RospotrebnadzorIrkutsk Antiplague Research Institute of RospotrebnadzorIrkutsk Antiplague Research Institute of RospotrebnadzorInfluence of Francisella tularensis lipopolysaccharide preparations on morphological changes in immunocompetent experimental animals was studied by subcutaneous introduction using survey microscopy and morphometric methods. Low expressed activation of B- and T-dependent bands in immunocompetent organs was determined. Proliferation of antigen-presented cells at early stages of investigation indicates the cell immunity activation. Pathomorphological alterations caused by lipopolysaccharide inoculation are homogeneous and benignant.https://www.actabiomedica.ru/jour/article/view/1693francisella tularensis lipopolysaccharideimmunocompetent organmorphometrymicroscopy |
| spellingShingle | S. A. Vityazeva T. P. Starovoytova V. I. Dubrovina A. S. Sorokoumova V. V. Voitkova V. B. Nikolaev S. A. Tatarnikov K. M. Korytov Changes in immunocompetent guinea pigs immunizing with Francisella Tularensislipopoly-saccharide Acta Biomedica Scientifica francisella tularensis lipopolysaccharide immunocompetent organ morphometry microscopy |
| title | Changes in immunocompetent guinea pigs immunizing with Francisella Tularensislipopoly-saccharide |
| title_full | Changes in immunocompetent guinea pigs immunizing with Francisella Tularensislipopoly-saccharide |
| title_fullStr | Changes in immunocompetent guinea pigs immunizing with Francisella Tularensislipopoly-saccharide |
| title_full_unstemmed | Changes in immunocompetent guinea pigs immunizing with Francisella Tularensislipopoly-saccharide |
| title_short | Changes in immunocompetent guinea pigs immunizing with Francisella Tularensislipopoly-saccharide |
| title_sort | changes in immunocompetent guinea pigs immunizing with francisella tularensislipopoly saccharide |
| topic | francisella tularensis lipopolysaccharide immunocompetent organ morphometry microscopy |
| url | https://www.actabiomedica.ru/jour/article/view/1693 |
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