A complicated presentation of vertebral coccidioidomycosis dissemination: A case report and discussion

Coccidioidomycosis, also known as San Joaquin Valley fever, is an illness caused by the dimorphic fungus Coccidioides. Coccidioidomycosis is endemic to desert regions of the Western Hemisphere, including California, Arizona, Utah, Nevada, and New Mexico. We report a case of disseminated coccidioidom...

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Main Authors: Zoe N. Anderson, BS, Kayla A. Aikins, BS, Benjamin L. Bosse, MS, Ryan W. Nolan, BS, Riyaa Rajesh, Rajesh Rangaswamy, MD, Karthikram Raghuram, MD
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Radiology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043323008506
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author Zoe N. Anderson, BS
Kayla A. Aikins, BS
Benjamin L. Bosse, MS
Ryan W. Nolan, BS
Riyaa Rajesh
Rajesh Rangaswamy, MD
Karthikram Raghuram, MD
author_facet Zoe N. Anderson, BS
Kayla A. Aikins, BS
Benjamin L. Bosse, MS
Ryan W. Nolan, BS
Riyaa Rajesh
Rajesh Rangaswamy, MD
Karthikram Raghuram, MD
author_sort Zoe N. Anderson, BS
collection DOAJ
description Coccidioidomycosis, also known as San Joaquin Valley fever, is an illness caused by the dimorphic fungus Coccidioides. Coccidioidomycosis is endemic to desert regions of the Western Hemisphere, including California, Arizona, Utah, Nevada, and New Mexico. We report a case of disseminated coccidioidomycosis in a 42-year-old male. Months after an upper respiratory infection of unidentified origin, the patient began experiencing back pain. The persistence of the back pain prompted MRI and CT imaging, which revealed lytic lesions. His clinical and radiological presentation mimicked, and was originally approached, as if it were a malignancy. Metastasis or multiple myeloma were considered the most likely differential diagnoses. As a result, the patient underwent surgical exploration. Pathology results indicated the presence of a fungal infection, without evidence of malignancy. PCR confirmed the diagnosis of coccidioidomycosis. The patient began treatment with fluconazole 800 mg daily and is anticipated to receive antifungal treatment for an indefinite period.
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spelling doaj.art-e206d64659084d518c97c0c473a20e3a2023-12-10T06:14:37ZengElsevierRadiology Case Reports1930-04332024-02-01192763767A complicated presentation of vertebral coccidioidomycosis dissemination: A case report and discussionZoe N. Anderson, BS0Kayla A. Aikins, BS1Benjamin L. Bosse, MS2Ryan W. Nolan, BS3Riyaa Rajesh4Rajesh Rangaswamy, MD5Karthikram Raghuram, MD6School of Medicine, University of Nevada, Reno, Reno, NV, USA; Corresponding author.School of Medicine, University of Nevada, Reno, Reno, NV, USASchool of Medicine, University of Nevada, Reno, Reno, NV, USASchool of Medicine, University of Nevada, Reno, Reno, NV, USAUniversity of Southern California, Los Angeles, CA, USAReno Radiological Associates, Reno, NV, USAReno Radiological Associates, Reno, NV, USACoccidioidomycosis, also known as San Joaquin Valley fever, is an illness caused by the dimorphic fungus Coccidioides. Coccidioidomycosis is endemic to desert regions of the Western Hemisphere, including California, Arizona, Utah, Nevada, and New Mexico. We report a case of disseminated coccidioidomycosis in a 42-year-old male. Months after an upper respiratory infection of unidentified origin, the patient began experiencing back pain. The persistence of the back pain prompted MRI and CT imaging, which revealed lytic lesions. His clinical and radiological presentation mimicked, and was originally approached, as if it were a malignancy. Metastasis or multiple myeloma were considered the most likely differential diagnoses. As a result, the patient underwent surgical exploration. Pathology results indicated the presence of a fungal infection, without evidence of malignancy. PCR confirmed the diagnosis of coccidioidomycosis. The patient began treatment with fluconazole 800 mg daily and is anticipated to receive antifungal treatment for an indefinite period.http://www.sciencedirect.com/science/article/pii/S1930043323008506Disseminated vertebral coccidioidomycosisSan Joaquin Valley feverCoccidioidesMalignancyMedication noncomplianceImmunocompromised
spellingShingle Zoe N. Anderson, BS
Kayla A. Aikins, BS
Benjamin L. Bosse, MS
Ryan W. Nolan, BS
Riyaa Rajesh
Rajesh Rangaswamy, MD
Karthikram Raghuram, MD
A complicated presentation of vertebral coccidioidomycosis dissemination: A case report and discussion
Radiology Case Reports
Disseminated vertebral coccidioidomycosis
San Joaquin Valley fever
Coccidioides
Malignancy
Medication noncompliance
Immunocompromised
title A complicated presentation of vertebral coccidioidomycosis dissemination: A case report and discussion
title_full A complicated presentation of vertebral coccidioidomycosis dissemination: A case report and discussion
title_fullStr A complicated presentation of vertebral coccidioidomycosis dissemination: A case report and discussion
title_full_unstemmed A complicated presentation of vertebral coccidioidomycosis dissemination: A case report and discussion
title_short A complicated presentation of vertebral coccidioidomycosis dissemination: A case report and discussion
title_sort complicated presentation of vertebral coccidioidomycosis dissemination a case report and discussion
topic Disseminated vertebral coccidioidomycosis
San Joaquin Valley fever
Coccidioides
Malignancy
Medication noncompliance
Immunocompromised
url http://www.sciencedirect.com/science/article/pii/S1930043323008506
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