Cardiac Damage and Conduction Disorders after Transcatheter Aortic Valve Implantation
Recently, a staging system using 4 grades has been proposed to quantify the extent of cardiac damage associated with aortic stenosis (AS), namely AS-related cardiac damage staging (ASCDS). ASCDS is independently associated with all-cause mortality and important clinical outcomes. To evaluate whether...
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MDPI AG
2024-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/13/2/409 |
| _version_ | 1797339714075754496 |
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| author | François Damas Mai-Linh Nguyen Trung Adriana Postolache Hélène Petitjean Mathieu Lempereur Tommaso Viva Cécile Oury Raluca Dulgheru Patrizio Lancellotti |
| author_facet | François Damas Mai-Linh Nguyen Trung Adriana Postolache Hélène Petitjean Mathieu Lempereur Tommaso Viva Cécile Oury Raluca Dulgheru Patrizio Lancellotti |
| author_sort | François Damas |
| collection | DOAJ |
| description | Recently, a staging system using 4 grades has been proposed to quantify the extent of cardiac damage associated with aortic stenosis (AS), namely AS-related cardiac damage staging (ASCDS). ASCDS is independently associated with all-cause mortality and important clinical outcomes. To evaluate whether it might be associated with the occurrence of conduction system disorders after TAVI, a total of 119 symptomatic patients with severe AS who underwent a TAVI were categorized according to ASCDS: group 1 (13.5%): no or LV damage; group 2 (58.8%): left atrial/mitral valve damage, atrial fibrillation (AF); group 3 (27.7%): low-flow state, pulmonary vasculature/tricuspid valve/RV damage. After TAVI, 34% of patients exhibited LBBB and 10% high-degree atrioventricular block (HD-AVB). No patient in group 1 developed HD-AVB whereas new LBBB was frequent in groups 2 and 3. Twenty-one patients presented with paroxysmal AF with a higher rate for each group increment (group 1: <i>n</i> = 0, 0%; group 2: <i>n</i> = 11, 15.7%; group 3: <i>n</i> = 10, 30.3%) (<i>p</i> = 0.012). Patients in group 3 had the higher rate of permanent pacemaker implantation (PPMI) (group 1: <i>n</i> = 1, 6.3%; group 2: <i>n</i> = 7, 10%; group 3: <i>n</i> = 9, 27.3%) (<i>p</i> = 0.012). In conclusion, ASCDS might help identify patients at higher risk of conduction disorders and PPMI requirement after TAVI. |
| first_indexed | 2024-03-08T09:52:22Z |
| format | Article |
| id | doaj.art-e20723a8f9774d0e96f5aedf6725b652 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-08T09:52:22Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-e20723a8f9774d0e96f5aedf6725b6522024-01-29T14:01:30ZengMDPI AGJournal of Clinical Medicine2077-03832024-01-0113240910.3390/jcm13020409Cardiac Damage and Conduction Disorders after Transcatheter Aortic Valve ImplantationFrançois Damas0Mai-Linh Nguyen Trung1Adriana Postolache2Hélène Petitjean3Mathieu Lempereur4Tommaso Viva5Cécile Oury6Raluca Dulgheru7Patrizio Lancellotti8Department of Cardiology, CHU Sart Tilman, GIGA Cardiovascular Sciences Liège, University of Liège Hospital, 4000 Liège, BelgiumDepartment of Cardiology, CHU Sart Tilman, GIGA Cardiovascular Sciences Liège, University of Liège Hospital, 4000 Liège, BelgiumDepartment of Cardiology, CHU Sart Tilman, GIGA Cardiovascular Sciences Liège, University of Liège Hospital, 4000 Liège, BelgiumDepartment of Cardiology, CHU Sart Tilman, GIGA Cardiovascular Sciences Liège, University of Liège Hospital, 4000 Liège, BelgiumDepartment of Cardiology, CHU Sart Tilman, GIGA Cardiovascular Sciences Liège, University of Liège Hospital, 4000 Liège, BelgiumDepartment of Cardiology, CHU Sart Tilman, GIGA Cardiovascular Sciences Liège, University of Liège Hospital, 4000 Liège, BelgiumDepartment of Cardiology, CHU Sart Tilman, GIGA Cardiovascular Sciences Liège, University of Liège Hospital, 4000 Liège, BelgiumDepartment of Cardiology, CHU Sart Tilman, GIGA Cardiovascular Sciences Liège, University of Liège Hospital, 4000 Liège, BelgiumDepartment of Cardiology, CHU Sart Tilman, GIGA Cardiovascular Sciences Liège, University of Liège Hospital, 4000 Liège, BelgiumRecently, a staging system using 4 grades has been proposed to quantify the extent of cardiac damage associated with aortic stenosis (AS), namely AS-related cardiac damage staging (ASCDS). ASCDS is independently associated with all-cause mortality and important clinical outcomes. To evaluate whether it might be associated with the occurrence of conduction system disorders after TAVI, a total of 119 symptomatic patients with severe AS who underwent a TAVI were categorized according to ASCDS: group 1 (13.5%): no or LV damage; group 2 (58.8%): left atrial/mitral valve damage, atrial fibrillation (AF); group 3 (27.7%): low-flow state, pulmonary vasculature/tricuspid valve/RV damage. After TAVI, 34% of patients exhibited LBBB and 10% high-degree atrioventricular block (HD-AVB). No patient in group 1 developed HD-AVB whereas new LBBB was frequent in groups 2 and 3. Twenty-one patients presented with paroxysmal AF with a higher rate for each group increment (group 1: <i>n</i> = 0, 0%; group 2: <i>n</i> = 11, 15.7%; group 3: <i>n</i> = 10, 30.3%) (<i>p</i> = 0.012). Patients in group 3 had the higher rate of permanent pacemaker implantation (PPMI) (group 1: <i>n</i> = 1, 6.3%; group 2: <i>n</i> = 7, 10%; group 3: <i>n</i> = 9, 27.3%) (<i>p</i> = 0.012). In conclusion, ASCDS might help identify patients at higher risk of conduction disorders and PPMI requirement after TAVI.https://www.mdpi.com/2077-0383/13/2/409TAVIcardiac damageconduction disordersrisk stratification |
| spellingShingle | François Damas Mai-Linh Nguyen Trung Adriana Postolache Hélène Petitjean Mathieu Lempereur Tommaso Viva Cécile Oury Raluca Dulgheru Patrizio Lancellotti Cardiac Damage and Conduction Disorders after Transcatheter Aortic Valve Implantation Journal of Clinical Medicine TAVI cardiac damage conduction disorders risk stratification |
| title | Cardiac Damage and Conduction Disorders after Transcatheter Aortic Valve Implantation |
| title_full | Cardiac Damage and Conduction Disorders after Transcatheter Aortic Valve Implantation |
| title_fullStr | Cardiac Damage and Conduction Disorders after Transcatheter Aortic Valve Implantation |
| title_full_unstemmed | Cardiac Damage and Conduction Disorders after Transcatheter Aortic Valve Implantation |
| title_short | Cardiac Damage and Conduction Disorders after Transcatheter Aortic Valve Implantation |
| title_sort | cardiac damage and conduction disorders after transcatheter aortic valve implantation |
| topic | TAVI cardiac damage conduction disorders risk stratification |
| url | https://www.mdpi.com/2077-0383/13/2/409 |
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