Role of DNA Methylation Profile in Diagnosing Astroblastoma: A Case Report and Literature Review

Role of DNA Methylation Profile in Diagnosing Astroblastoma: A Case Report and Literature Review

Astroblastoma is a rare tumor of the central nervous system (CNS) with uncertain clinical behavior. Recently, DNA methylation profiling has been shown to provide a highly robust and reproducible approach for the classification of all CNS tumors across different age groups. By using DNA methylation p...

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Bibliographic Details
Main Authors: Giuseppe Petruzzellis, Iside Alessi, Giovanna Stefania Colafati, Francesca Diomedi-Camassei, Andrea Ciolfi, Lucia Pedace, Antonella Cacchione, Andrea Carai, Marco Tartaglia, Angela Mastronuzzi, Evelina Miele
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
astroblastoma
DNA methylation profiling
brain tumor
next-generation sequencing
CNS-HGNET-MN1
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00391/full

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