EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS
BACKGROUND. Acute poisonings with cauterant agents are accompanied by an increase in acidforming function of the stomach in more than half of the cases. It slows reparative processes in the gastric wall and increases the risk of complications.MATERIALS AND METHODS. The study involved 40 patients wi...
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Format: | Article |
Language: | Russian |
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Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
2016-03-01
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Series: | Неотложная медицинская помощь |
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Online Access: | https://www.jnmp.ru/jour/article/view/228 |
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author | K. K. Ilyashenko M. V. Belova I. S. Kashtanova |
author_facet | K. K. Ilyashenko M. V. Belova I. S. Kashtanova |
author_sort | K. K. Ilyashenko |
collection | DOAJ |
description | BACKGROUND. Acute poisonings with cauterant agents are accompanied by an increase in acidforming function of the stomach in more than half of the cases. It slows reparative processes in the gastric wall and increases the risk of complications.MATERIALS AND METHODS. The study involved 40 patients with chemical burns of the stomach grade IIIIV who had underwent standard therapy. The complex therapy for 20 patients included 5 days of intravenous Rabeloc, 20 mg daily.RESULTS. Rabeloc included into the complex of therapeutic measures in patients with chemical burns of the stomach grade III–IV helped reduce the length of stay in the ICU by 1.5 times and inpatient treatment by 1.8 times, reduce the frequency of early secondary hemorrhage and decompensated cicatricial narrowing of the stomach.CONCLUSION. Early parenteral use of Rabeloc increases the effectiveness of complex therapy for acute poisoning with cauterant substances. |
first_indexed | 2024-03-12T18:15:42Z |
format | Article |
id | doaj.art-e20c9d57e99d45759c7d7070a6274e32 |
institution | Directory Open Access Journal |
issn | 2223-9022 2541-8017 |
language | Russian |
last_indexed | 2024-03-12T18:15:42Z |
publishDate | 2016-03-01 |
publisher | Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department |
record_format | Article |
series | Неотложная медицинская помощь |
spelling | doaj.art-e20c9d57e99d45759c7d7070a6274e322023-08-02T09:09:44ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172016-03-01035659226EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTSK. K. Ilyashenko0M. V. Belova1I. S. Kashtanova2N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, MoscowBACKGROUND. Acute poisonings with cauterant agents are accompanied by an increase in acidforming function of the stomach in more than half of the cases. It slows reparative processes in the gastric wall and increases the risk of complications.MATERIALS AND METHODS. The study involved 40 patients with chemical burns of the stomach grade IIIIV who had underwent standard therapy. The complex therapy for 20 patients included 5 days of intravenous Rabeloc, 20 mg daily.RESULTS. Rabeloc included into the complex of therapeutic measures in patients with chemical burns of the stomach grade III–IV helped reduce the length of stay in the ICU by 1.5 times and inpatient treatment by 1.8 times, reduce the frequency of early secondary hemorrhage and decompensated cicatricial narrowing of the stomach.CONCLUSION. Early parenteral use of Rabeloc increases the effectiveness of complex therapy for acute poisoning with cauterant substances.https://www.jnmp.ru/jour/article/view/228chemical burn of the stomachproton pump inhibitors |
spellingShingle | K. K. Ilyashenko M. V. Belova I. S. Kashtanova EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS Неотложная медицинская помощь chemical burn of the stomach proton pump inhibitors |
title | EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS |
title_full | EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS |
title_fullStr | EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS |
title_full_unstemmed | EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS |
title_short | EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS |
title_sort | early parenteral use of proton pump inhibitors in the complex treatment of acute poisoning with cauterant agents |
topic | chemical burn of the stomach proton pump inhibitors |
url | https://www.jnmp.ru/jour/article/view/228 |
work_keys_str_mv | AT kkilyashenko earlyparenteraluseofprotonpumpinhibitorsinthecomplextreatmentofacutepoisoningwithcauterantagents AT mvbelova earlyparenteraluseofprotonpumpinhibitorsinthecomplextreatmentofacutepoisoningwithcauterantagents AT iskashtanova earlyparenteraluseofprotonpumpinhibitorsinthecomplextreatmentofacutepoisoningwithcauterantagents |