EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS

BACKGROUND. Acute poisonings with cauterant agents are accompanied by an increase in acid­forming function of the stomach in more than half of the cases. It slows reparative processes in the gastric wall and increases the risk of complications.MATERIALS AND METHODS. The study involved 40 patients wi...

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Main Authors: K. K. Ilyashenko, M. V. Belova, I. S. Kashtanova
Format: Article
Language:Russian
Published: Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department 2016-03-01
Series:Неотложная медицинская помощь
Subjects:
Online Access:https://www.jnmp.ru/jour/article/view/228
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author K. K. Ilyashenko
M. V. Belova
I. S. Kashtanova
author_facet K. K. Ilyashenko
M. V. Belova
I. S. Kashtanova
author_sort K. K. Ilyashenko
collection DOAJ
description BACKGROUND. Acute poisonings with cauterant agents are accompanied by an increase in acid­forming function of the stomach in more than half of the cases. It slows reparative processes in the gastric wall and increases the risk of complications.MATERIALS AND METHODS. The study involved 40 patients with chemical burns of the stomach grade III­IV who had underwent standard therapy. The complex therapy for 20 patients included 5 days of intravenous Rabeloc, 20 mg daily.RESULTS. Rabeloc included into the complex of therapeutic measures in patients with chemical burns of the stomach grade III–IV helped reduce the length of stay in the ICU by 1.5 times and inpatient treatment by 1.8 times, reduce the frequency of early secondary hemorrhage and decompensated cicatricial narrowing of the stomach.CONCLUSION. Early parenteral use of Rabeloc increases the effectiveness of complex therapy for acute poisoning with cauterant substances.
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spelling doaj.art-e20c9d57e99d45759c7d7070a6274e322023-08-02T09:09:44ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172016-03-01035659226EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTSK. K. Ilyashenko0M. V. Belova1I. S. Kashtanova2N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, MoscowBACKGROUND. Acute poisonings with cauterant agents are accompanied by an increase in acid­forming function of the stomach in more than half of the cases. It slows reparative processes in the gastric wall and increases the risk of complications.MATERIALS AND METHODS. The study involved 40 patients with chemical burns of the stomach grade III­IV who had underwent standard therapy. The complex therapy for 20 patients included 5 days of intravenous Rabeloc, 20 mg daily.RESULTS. Rabeloc included into the complex of therapeutic measures in patients with chemical burns of the stomach grade III–IV helped reduce the length of stay in the ICU by 1.5 times and inpatient treatment by 1.8 times, reduce the frequency of early secondary hemorrhage and decompensated cicatricial narrowing of the stomach.CONCLUSION. Early parenteral use of Rabeloc increases the effectiveness of complex therapy for acute poisoning with cauterant substances.https://www.jnmp.ru/jour/article/view/228chemical burn of the stomachproton pump inhibitors
spellingShingle K. K. Ilyashenko
M. V. Belova
I. S. Kashtanova
EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS
Неотложная медицинская помощь
chemical burn of the stomach
proton pump inhibitors
title EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS
title_full EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS
title_fullStr EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS
title_full_unstemmed EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS
title_short EARLY PARENTERAL USE OF PROTON PUMP INHIBITORS IN THE COMPLEx TREATMENT OF ACUTE POISONING WITH CAUTERANT AGENTS
title_sort early parenteral use of proton pump inhibitors in the complex treatment of acute poisoning with cauterant agents
topic chemical burn of the stomach
proton pump inhibitors
url https://www.jnmp.ru/jour/article/view/228
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AT mvbelova earlyparenteraluseofprotonpumpinhibitorsinthecomplextreatmentofacutepoisoningwithcauterantagents
AT iskashtanova earlyparenteraluseofprotonpumpinhibitorsinthecomplextreatmentofacutepoisoningwithcauterantagents