Clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0.5% levobupivacaine in ultrasonography assisted supraclavicular brachial plexus block
Background: Ultrasonography-assisted supraclavicular block is an efficacious and practical method and allows us to use a lower volume of local anesthetic in compactly arranged brachial plexus. The study envisioned evaluating the analgesic and anesthetic effects of Inj. dexamethasone (8mg) as an adju...
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| Format: | Article |
| Language: | English |
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Creative Pharma Assent
2022-12-01
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| Series: | Journal of Applied Pharmaceutical Research |
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| Online Access: | https://japtronline.com/index.php/joapr/article/view/285 |
| _version_ | 1797842738610176000 |
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| author | Chetali Das Rajni Mathur Srishti Kukreja |
| author_facet | Chetali Das Rajni Mathur Srishti Kukreja |
| author_sort | Chetali Das |
| collection | DOAJ |
| description | Background: Ultrasonography-assisted supraclavicular block is an efficacious and practical method and allows us to use a lower volume of local anesthetic in compactly arranged brachial plexus. The study envisioned evaluating the analgesic and anesthetic effects of Inj. dexamethasone (8mg) as an adjuvant to 0.5% levobupivacaine to determine the time for first rescue analgesia and number of rescue analgesics needed in 24 hours duration in brachial plexus blockade in adult patients listed for upper limb surgeries. Results: This prospective randomized double-blind interventional study was carried out in ASAI and II, aged 20 to 55 years. In group A (n=30) Inj. Levobupivacaine 20ml and Inj. Normal saline 2ml was given. In group B (n=30) Inj. Levobupivacaine 20ml and Inj. Dexamethasone 2ml was given. The time for the demand of the first rescue analgesia was 431.50 ± 46.15 minutes in group A and 749.38 ± 62.41 minutes in group B, with a p-value < 0.001. The demand for rescue analgesics was more in Group A in contrast to Group B. Conclusion: We deduce with our study, with the addition of dexamethasone, the time for rescue analgesia is prolonged, and the number of rescue analgesic demands is reduced, with a faster onset and extended duration of both sensory and motor block. |
| first_indexed | 2024-04-09T16:54:12Z |
| format | Article |
| id | doaj.art-e20ca8f6ebbf4b109d011cb6eba49b98 |
| institution | Directory Open Access Journal |
| issn | 2348-0335 |
| language | English |
| last_indexed | 2024-04-09T16:54:12Z |
| publishDate | 2022-12-01 |
| publisher | Creative Pharma Assent |
| record_format | Article |
| series | Journal of Applied Pharmaceutical Research |
| spelling | doaj.art-e20ca8f6ebbf4b109d011cb6eba49b982023-04-21T09:28:16ZengCreative Pharma AssentJournal of Applied Pharmaceutical Research2348-03352022-12-01104141810.18231/j.joapr.2022.10.4.14.18286Clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0.5% levobupivacaine in ultrasonography assisted supraclavicular brachial plexus blockChetali Das0https://orcid.org/0000-0002-2689-0123Rajni Mathur1Srishti Kukreja2https://orcid.org/0000-0001-8616-6017Department of Anaesthesiology and Critical Care, S.M.S. Medical College and Attached Group of Hospitals, Sawai Mansingh road, Jaipur, 302004Department of Anaesthesiology and Critical Care, S.M.S. Medical College and Attached Group of Hospitals, Sawai Mansingh road, Jaipur, 302004Department of Anaesthesiology and Critical Care, S.M.S. Medical College and Attached Group of Hospitals, Sawai Mansingh road, Jaipur, 302004Background: Ultrasonography-assisted supraclavicular block is an efficacious and practical method and allows us to use a lower volume of local anesthetic in compactly arranged brachial plexus. The study envisioned evaluating the analgesic and anesthetic effects of Inj. dexamethasone (8mg) as an adjuvant to 0.5% levobupivacaine to determine the time for first rescue analgesia and number of rescue analgesics needed in 24 hours duration in brachial plexus blockade in adult patients listed for upper limb surgeries. Results: This prospective randomized double-blind interventional study was carried out in ASAI and II, aged 20 to 55 years. In group A (n=30) Inj. Levobupivacaine 20ml and Inj. Normal saline 2ml was given. In group B (n=30) Inj. Levobupivacaine 20ml and Inj. Dexamethasone 2ml was given. The time for the demand of the first rescue analgesia was 431.50 ± 46.15 minutes in group A and 749.38 ± 62.41 minutes in group B, with a p-value < 0.001. The demand for rescue analgesics was more in Group A in contrast to Group B. Conclusion: We deduce with our study, with the addition of dexamethasone, the time for rescue analgesia is prolonged, and the number of rescue analgesic demands is reduced, with a faster onset and extended duration of both sensory and motor block.https://japtronline.com/index.php/joapr/article/view/285levobupivacainedexamethasoneultrasonographysupraclavicular blocklow volume |
| spellingShingle | Chetali Das Rajni Mathur Srishti Kukreja Clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0.5% levobupivacaine in ultrasonography assisted supraclavicular brachial plexus block Journal of Applied Pharmaceutical Research levobupivacaine dexamethasone ultrasonography supraclavicular block low volume |
| title | Clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0.5% levobupivacaine in ultrasonography assisted supraclavicular brachial plexus block |
| title_full | Clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0.5% levobupivacaine in ultrasonography assisted supraclavicular brachial plexus block |
| title_fullStr | Clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0.5% levobupivacaine in ultrasonography assisted supraclavicular brachial plexus block |
| title_full_unstemmed | Clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0.5% levobupivacaine in ultrasonography assisted supraclavicular brachial plexus block |
| title_short | Clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0.5% levobupivacaine in ultrasonography assisted supraclavicular brachial plexus block |
| title_sort | clinical comparison of analgesic efficacy of addition of injection dexamethasone 8mg to 20ml 0 5 levobupivacaine in ultrasonography assisted supraclavicular brachial plexus block |
| topic | levobupivacaine dexamethasone ultrasonography supraclavicular block low volume |
| url | https://japtronline.com/index.php/joapr/article/view/285 |
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