Parameter estimates of the 2016-2017 Zika outbreak in Costa Rica: An Approximate Bayesian Computation (ABC) approach

In Costa Rica, the first known cases of Zika were reported in 2016. We looked at the 2016-2017 Zika outbreak and explored the transmission dynamics using weekly reported data. A nonlinear differential equation single-outbreak model with sexual transmission, as well as host availability for vector-fe...

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Bibliographic Details
Main Authors: Fabio Sanchez, Luis A. Barboza, Paola Vásquez
Format: Article
Language:English
Published: AIMS Press 2019-03-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/10.3934/mbe.2019136?viewType=HTML
Description
Summary:In Costa Rica, the first known cases of Zika were reported in 2016. We looked at the 2016-2017 Zika outbreak and explored the transmission dynamics using weekly reported data. A nonlinear differential equation single-outbreak model with sexual transmission, as well as host availability for vector-feeding was used to estimate key parameters, fit the data and compute the <i>basic reproductive number</i>, $\mathcal{R}_0$, distribution. Furthermore, a sensitivity and elasticity analysis was computed based on the $\mathcal{R}_0$ parameters
ISSN:1551-0018