Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent

An efficient one-pot synthesis of polyhydroacridines and polyhydroquinolines through the Hantzsch reaction in deep eutectic solvent choline chloride/urea (1:2) has been developed. Good to excellent yields, broad substrate compatibility as well as the reusability of the solvent are the major advantag...

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Main Authors: Wang Liang, Zhu Kai-Qiang, Chen Qun, He Ming-Yang
Format: Article
Language:English
Published: De Gruyter 2014-12-01
Series:Green Processing and Synthesis
Subjects:
Online Access:https://doi.org/10.1515/gps-2014-0056
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author Wang Liang
Zhu Kai-Qiang
Chen Qun
He Ming-Yang
author_facet Wang Liang
Zhu Kai-Qiang
Chen Qun
He Ming-Yang
author_sort Wang Liang
collection DOAJ
description An efficient one-pot synthesis of polyhydroacridines and polyhydroquinolines through the Hantzsch reaction in deep eutectic solvent choline chloride/urea (1:2) has been developed. Good to excellent yields, broad substrate compatibility as well as the reusability of the solvent are the major advantages of the present protocol.
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spelling doaj.art-e218265d84a24453b232832a356406c12022-12-21T18:34:24ZengDe GruyterGreen Processing and Synthesis2191-95422191-95502014-12-013645746110.1515/gps-2014-0056Facile and green synthesis of Hantzsch derivatives in deep eutectic solventWang Liang0Zhu Kai-Qiang1Chen Qun2He Ming-Yang3School of Petrochemical Engineering, Changzhou University, Changzhou 213164, People’s Republic of ChinaSchool of Petrochemical Engineering, Changzhou University, Changzhou 213164, People’s Republic of ChinaSchool of Petrochemical Engineering, Changzhou University, Changzhou 213164, People’s Republic of ChinaSchool of Petrochemical Engineering, Changzhou University, Changzhou 213164, People’s Republic of ChinaAn efficient one-pot synthesis of polyhydroacridines and polyhydroquinolines through the Hantzsch reaction in deep eutectic solvent choline chloride/urea (1:2) has been developed. Good to excellent yields, broad substrate compatibility as well as the reusability of the solvent are the major advantages of the present protocol.https://doi.org/10.1515/gps-2014-0056deep eutectic solventgreen chemistryhantzsch reactionpolyhydroacridinespolyhydroquinolines
spellingShingle Wang Liang
Zhu Kai-Qiang
Chen Qun
He Ming-Yang
Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent
Green Processing and Synthesis
deep eutectic solvent
green chemistry
hantzsch reaction
polyhydroacridines
polyhydroquinolines
title Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent
title_full Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent
title_fullStr Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent
title_full_unstemmed Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent
title_short Facile and green synthesis of Hantzsch derivatives in deep eutectic solvent
title_sort facile and green synthesis of hantzsch derivatives in deep eutectic solvent
topic deep eutectic solvent
green chemistry
hantzsch reaction
polyhydroacridines
polyhydroquinolines
url https://doi.org/10.1515/gps-2014-0056
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AT chenqun facileandgreensynthesisofhantzschderivativesindeepeutecticsolvent
AT hemingyang facileandgreensynthesisofhantzschderivativesindeepeutecticsolvent