Nuclear and cytoplasmic accumulation of Ep-ICD is frequently detected in human epithelial cancers.

Nuclear and cytoplasmic accumulation of Ep-ICD is frequently detected in human epithelial cancers.

We previously demonstrated that nuclear and cytoplasmic accumulation of the intracellular domain (Ep-ICD) of epithelial cell adhesion molecule (EpCAM) accompanied by a reciprocal reduction of its extracellular domain (EpEx), occurs in aggressive thyroid cancers. This study was designed to determine...

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Bibliographic Details
Main Authors: Ranju Ralhan, Helen C-H He, Anthony K-C So, Satyendra C Tripathi, Manish Kumar, Md Raghibul Hasan, Jatinder Kaur, Lawrence Kashat, Christina MacMillan, Shyam Singh Chauhan, Jeremy L Freeman, Paul G Walfish
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2994724?pdf=render

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