Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipient

Patients facing severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infections with comorbidities, especially patients whose immune system is weakened have higher chances to face severe outcomes. One of the main reasons behind the suppression of the immune system is iatrogenic, in patients...

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Main Authors: Dorina Supák, Balázs Mészáros, Márta Nagy, Dániel Gáspár, László J. Wagner, Zoltán Kukor, Sándor Valent
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.948025/full
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author Dorina Supák
Balázs Mészáros
Márta Nagy
Dániel Gáspár
László J. Wagner
Zoltán Kukor
Sándor Valent
author_facet Dorina Supák
Balázs Mészáros
Márta Nagy
Dániel Gáspár
László J. Wagner
Zoltán Kukor
Sándor Valent
author_sort Dorina Supák
collection DOAJ
description Patients facing severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infections with comorbidities, especially patients whose immune system is weakened have higher chances to face severe outcomes. One of the main reasons behind the suppression of the immune system is iatrogenic, in patients who have autoimmune diseases and/or had an organ transplant. Although there are studies that are examining immunocompromised and/or transplanted patients with COVID-19 infection, furthermore there is a limited number of studies available which are dealing with COVID-19 in pregnant women; however, it is unique and is worth reporting when these factors are coexisting. In this study, we present the case of a 33-year-old Caucasian pregnant woman, who had a kidney transplant in 2009 and contracted the SARS-CoV-2 virus on the 26th gestational week, in 2021. After her infection, superimposed preeclampsia was diagnosed and due to the worsening flowmetric parameters, she gave birth to a premature male newborn with cesarean section. Our kidney transplant patient’s case highlights how COVID-19 disease can lead to preeclampsia and artificial termination of gestation.
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spelling doaj.art-e22488ec53974fceaa001118346533442022-12-22T04:31:08ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-08-01910.3389/fmed.2022.948025948025Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipientDorina Supák0Balázs Mészáros1Márta Nagy2Dániel Gáspár3László J. Wagner4Zoltán Kukor5Sándor Valent6Department of Obstetrics and Gynecology, Semmelweis University, Budapest, HungaryDepartment of Obstetrics and Gynecology, Semmelweis University, Budapest, HungaryDepartment of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, Budapest, HungaryDepartment of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, Budapest, HungaryDepartment of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, HungaryDepartment of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, Budapest, HungaryDepartment of Obstetrics and Gynecology, Semmelweis University, Budapest, HungaryPatients facing severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infections with comorbidities, especially patients whose immune system is weakened have higher chances to face severe outcomes. One of the main reasons behind the suppression of the immune system is iatrogenic, in patients who have autoimmune diseases and/or had an organ transplant. Although there are studies that are examining immunocompromised and/or transplanted patients with COVID-19 infection, furthermore there is a limited number of studies available which are dealing with COVID-19 in pregnant women; however, it is unique and is worth reporting when these factors are coexisting. In this study, we present the case of a 33-year-old Caucasian pregnant woman, who had a kidney transplant in 2009 and contracted the SARS-CoV-2 virus on the 26th gestational week, in 2021. After her infection, superimposed preeclampsia was diagnosed and due to the worsening flowmetric parameters, she gave birth to a premature male newborn with cesarean section. Our kidney transplant patient’s case highlights how COVID-19 disease can lead to preeclampsia and artificial termination of gestation.https://www.frontiersin.org/articles/10.3389/fmed.2022.948025/fullCOVID-19SARS-CoV-2kidney transplantpregnancypreeclampsiainterleukin-6
spellingShingle Dorina Supák
Balázs Mészáros
Márta Nagy
Dániel Gáspár
László J. Wagner
Zoltán Kukor
Sándor Valent
Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipient
Frontiers in Medicine
COVID-19
SARS-CoV-2
kidney transplant
pregnancy
preeclampsia
interleukin-6
title Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipient
title_full Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipient
title_fullStr Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipient
title_full_unstemmed Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipient
title_short Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipient
title_sort case report covid 19 infection in a pregnant 33 year old kidney transplant recipient
topic COVID-19
SARS-CoV-2
kidney transplant
pregnancy
preeclampsia
interleukin-6
url https://www.frontiersin.org/articles/10.3389/fmed.2022.948025/full
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