Translating proteome and transcriptome dynamics of periodontal ligament stem cell-derived secretome/conditioned medium in an in vitro model of periodontitis

Translating proteome and transcriptome dynamics of periodontal ligament stem cell-derived secretome/conditioned medium in an in vitro model of periodontitis

Abstract Background Periodontal ligament stem cells (PDLSCs) have been proposed as therapeutic candidates in periodontal diseases and periodontium defects. Paracrine factors of PDLSCs, namely, secretome, can contribute to tissue regeneration comparable to direct stem cell application. This study exp...

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Bibliographic Details
Main Authors: Han Na Suh, Ju Young Ji, Jung Sun Heo
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Oral Health
Subjects:
Periodontal ligament stem cells
Secretome/conditioned medium
Osteogenic differentiation
Proteomic and transcriptomic profiling
Online Access:https://doi.org/10.1186/s12903-024-04167-z

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