Designing of Nanomaterials-Based Enzymatic Biosensors: Synthesis, Properties, and Applications
Among the many biological entities employed in the development of biosensors, enzymes have attracted the most attention. Nanotechnology has been fostering excellent prospects in the development of enzymatic biosensors, since enzyme immobilization onto conductive nanostructures can improve characteri...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Electrochem |
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| Online Access: | https://www.mdpi.com/2673-3293/2/1/12 |
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| author | Francisco T. T. Cavalcante Italo R. de A. Falcão José E. da S. Souza Thales G. Rocha Isamayra G. de Sousa Antônio L. G. Cavalcante André L. B. de Oliveira Maria C. M. de Sousa José C. S. dos Santos |
| author_facet | Francisco T. T. Cavalcante Italo R. de A. Falcão José E. da S. Souza Thales G. Rocha Isamayra G. de Sousa Antônio L. G. Cavalcante André L. B. de Oliveira Maria C. M. de Sousa José C. S. dos Santos |
| author_sort | Francisco T. T. Cavalcante |
| collection | DOAJ |
| description | Among the many biological entities employed in the development of biosensors, enzymes have attracted the most attention. Nanotechnology has been fostering excellent prospects in the development of enzymatic biosensors, since enzyme immobilization onto conductive nanostructures can improve characteristics that are crucial in biosensor transduction, such as surface-to-volume ratio, signal response, selectivity, sensitivity, conductivity, and biocatalytic activity, among others. These and other advantages of nanomaterial-based enzymatic biosensors are discussed in this work via the compilation of several reports on their applications in different industrial segments. To provide detailed insights into the state of the art of this technology, all the relevant concepts around the topic are discussed, including the properties of enzymes, the mechanisms involved in their immobilization, and the application of different enzyme-derived biosensors and nanomaterials. Finally, there is a discussion around the pressing challenges in this technology, which will be useful for guiding the development of future research in the area. |
| first_indexed | 2024-03-10T13:18:49Z |
| format | Article |
| id | doaj.art-e225ab9942eb4d749e8942f2184975fb |
| institution | Directory Open Access Journal |
| issn | 2673-3293 |
| language | English |
| last_indexed | 2024-03-10T13:18:49Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Electrochem |
| spelling | doaj.art-e225ab9942eb4d749e8942f2184975fb2023-11-21T10:12:10ZengMDPI AGElectrochem2673-32932021-03-012114918410.3390/electrochem2010012Designing of Nanomaterials-Based Enzymatic Biosensors: Synthesis, Properties, and ApplicationsFrancisco T. T. Cavalcante0Italo R. de A. Falcão1José E. da S. Souza2Thales G. Rocha3Isamayra G. de Sousa4Antônio L. G. Cavalcante5André L. B. de Oliveira6Maria C. M. de Sousa7José C. S. dos Santos8Departamento de Engenharia Química, Campus do Pici, Universidade Federal do Ceará, Bloco 709, Fortaleza 60455760, CE, BrazilCampus das Auroras, Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Redenção 62790970, CE, BrazilCampus das Auroras, Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Redenção 62790970, CE, BrazilCampus das Auroras, Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Redenção 62790970, CE, BrazilCampus das Auroras, Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Redenção 62790970, CE, BrazilDepartamento de Química Analítica e Físico-Química, Campus do Pici, Universidade Federal do Ceará, Bloco 940, Fortaleza 60455760, CE, BrazilDepartamento de Engenharia Química, Campus do Pici, Universidade Federal do Ceará, Bloco 709, Fortaleza 60455760, CE, BrazilCampus das Auroras, Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Redenção 62790970, CE, BrazilDepartamento de Engenharia Química, Campus do Pici, Universidade Federal do Ceará, Bloco 709, Fortaleza 60455760, CE, BrazilAmong the many biological entities employed in the development of biosensors, enzymes have attracted the most attention. Nanotechnology has been fostering excellent prospects in the development of enzymatic biosensors, since enzyme immobilization onto conductive nanostructures can improve characteristics that are crucial in biosensor transduction, such as surface-to-volume ratio, signal response, selectivity, sensitivity, conductivity, and biocatalytic activity, among others. These and other advantages of nanomaterial-based enzymatic biosensors are discussed in this work via the compilation of several reports on their applications in different industrial segments. To provide detailed insights into the state of the art of this technology, all the relevant concepts around the topic are discussed, including the properties of enzymes, the mechanisms involved in their immobilization, and the application of different enzyme-derived biosensors and nanomaterials. Finally, there is a discussion around the pressing challenges in this technology, which will be useful for guiding the development of future research in the area.https://www.mdpi.com/2673-3293/2/1/12biosensorsnanomaterialsenzyme immobilization |
| spellingShingle | Francisco T. T. Cavalcante Italo R. de A. Falcão José E. da S. Souza Thales G. Rocha Isamayra G. de Sousa Antônio L. G. Cavalcante André L. B. de Oliveira Maria C. M. de Sousa José C. S. dos Santos Designing of Nanomaterials-Based Enzymatic Biosensors: Synthesis, Properties, and Applications Electrochem biosensors nanomaterials enzyme immobilization |
| title | Designing of Nanomaterials-Based Enzymatic Biosensors: Synthesis, Properties, and Applications |
| title_full | Designing of Nanomaterials-Based Enzymatic Biosensors: Synthesis, Properties, and Applications |
| title_fullStr | Designing of Nanomaterials-Based Enzymatic Biosensors: Synthesis, Properties, and Applications |
| title_full_unstemmed | Designing of Nanomaterials-Based Enzymatic Biosensors: Synthesis, Properties, and Applications |
| title_short | Designing of Nanomaterials-Based Enzymatic Biosensors: Synthesis, Properties, and Applications |
| title_sort | designing of nanomaterials based enzymatic biosensors synthesis properties and applications |
| topic | biosensors nanomaterials enzyme immobilization |
| url | https://www.mdpi.com/2673-3293/2/1/12 |
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