scReQTL: an approach to correlate SNVs to gene expression from individual scRNA-seq datasets

scReQTL: an approach to correlate SNVs to gene expression from individual scRNA-seq datasets

Abstract Background Recently, pioneering expression quantitative trait loci (eQTL) studies on single cell RNA sequencing (scRNA-seq) data have revealed new and cell-specific regulatory single nucleotide variants (SNVs). Here, we present an alternative QTL-related approach applicable to transcribed S...

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Bibliographic Details
Main Authors: Hongyu Liu, N. M. Prashant, Liam F. Spurr, Pavlos Bousounis, Nawaf Alomran, Helen Ibeawuchi, Justin Sein, Piotr Słowiński, Krasimira Tsaneva-Atanasova, Anelia Horvath
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Genomics
Subjects:
eQTL, ReQTL, scReQTL, single cell
VAFRNA
scVAFRNA
scRNA-seq
SNV
Genetic variation
Online Access:https://doi.org/10.1186/s12864-020-07334-y

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