LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration

LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration

BackgroundLIM domain only 2 (LMO2, human gene) is a key transcription factor that regulates hematopoiesis and vascular development. However, its role in adult endothelial function has been incompletely characterized. Methods and ResultsIn vitro loss‐ and gain‐of‐function studies on LMO2 were perform...

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Bibliographic Details
Main Authors: Shu Meng, Gianfranco Matrone, Jie Lv, Kaifu Chen, Wing Tak Wong, John P. Cooke
Format: Article
Language:English
Published: Wiley 2016-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
angiogenesis
endothelial cell
LIM domain only 2
proliferation
regeneration
transcription factors
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.004117

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