Short-term molecular consequences of chromosome mis-segregation for genome stability
Chromosomal instability leads to aneuploidy, a state of karyotype imbalance. By inducing controlled chromosome mis-segregation, Santaguida and colleagues show that aneuploidy can also instigate chromosomal instability.
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-37095-7 |
| _version_ | 1797864316629680128 |
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| author | Lorenza Garribba Giuseppina De Feudis Valentino Martis Martina Galli Marie Dumont Yonatan Eliezer René Wardenaar Marica Rosaria Ippolito Divya Ramalingam Iyer Andréa E. Tijhuis Diana C. J. Spierings Michael Schubert Silvia Taglietti Chiara Soriani Simon Gemble Renata Basto Nick Rhind Floris Foijer Uri Ben-David Daniele Fachinetti Ylli Doksani Stefano Santaguida |
| author_facet | Lorenza Garribba Giuseppina De Feudis Valentino Martis Martina Galli Marie Dumont Yonatan Eliezer René Wardenaar Marica Rosaria Ippolito Divya Ramalingam Iyer Andréa E. Tijhuis Diana C. J. Spierings Michael Schubert Silvia Taglietti Chiara Soriani Simon Gemble Renata Basto Nick Rhind Floris Foijer Uri Ben-David Daniele Fachinetti Ylli Doksani Stefano Santaguida |
| author_sort | Lorenza Garribba |
| collection | DOAJ |
| description | Chromosomal instability leads to aneuploidy, a state of karyotype imbalance. By inducing controlled chromosome mis-segregation, Santaguida and colleagues show that aneuploidy can also instigate chromosomal instability. |
| first_indexed | 2024-04-09T22:50:56Z |
| format | Article |
| id | doaj.art-e226f0a659b0484e8d7815070b875a08 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-09T22:50:56Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e226f0a659b0484e8d7815070b875a082023-03-22T11:40:12ZengNature PortfolioNature Communications2041-17232023-03-0114111710.1038/s41467-023-37095-7Short-term molecular consequences of chromosome mis-segregation for genome stabilityLorenza Garribba0Giuseppina De Feudis1Valentino Martis2Martina Galli3Marie Dumont4Yonatan Eliezer5René Wardenaar6Marica Rosaria Ippolito7Divya Ramalingam Iyer8Andréa E. Tijhuis9Diana C. J. Spierings10Michael Schubert11Silvia Taglietti12Chiara Soriani13Simon Gemble14Renata Basto15Nick Rhind16Floris Foijer17Uri Ben-David18Daniele Fachinetti19Ylli Doksani20Stefano Santaguida21Department of Experimental Oncology at IEO, European Institute of Oncology IRCCSDepartment of Experimental Oncology at IEO, European Institute of Oncology IRCCSDepartment of Experimental Oncology at IEO, European Institute of Oncology IRCCSIFOM ETS - The AIRC Institute of Molecular OncologyInstitut Curie, PSL Research University, CNRSDepartment of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv UniversityEuropean Research Institute for the Biology of Ageing, University of Groningen, University Medical Center GroningenDepartment of Experimental Oncology at IEO, European Institute of Oncology IRCCSDepartment of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical SchoolEuropean Research Institute for the Biology of Ageing, University of Groningen, University Medical Center GroningenEuropean Research Institute for the Biology of Ageing, University of Groningen, University Medical Center GroningenEuropean Research Institute for the Biology of Ageing, University of Groningen, University Medical Center GroningenDepartment of Experimental Oncology at IEO, European Institute of Oncology IRCCSDepartment of Experimental Oncology at IEO, European Institute of Oncology IRCCSInstitut Curie, PSL Research University, CNRSInstitut Curie, PSL Research University, CNRSDepartment of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical SchoolEuropean Research Institute for the Biology of Ageing, University of Groningen, University Medical Center GroningenDepartment of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv UniversityInstitut Curie, PSL Research University, CNRSIFOM ETS - The AIRC Institute of Molecular OncologyDepartment of Experimental Oncology at IEO, European Institute of Oncology IRCCSChromosomal instability leads to aneuploidy, a state of karyotype imbalance. By inducing controlled chromosome mis-segregation, Santaguida and colleagues show that aneuploidy can also instigate chromosomal instability.https://doi.org/10.1038/s41467-023-37095-7 |
| spellingShingle | Lorenza Garribba Giuseppina De Feudis Valentino Martis Martina Galli Marie Dumont Yonatan Eliezer René Wardenaar Marica Rosaria Ippolito Divya Ramalingam Iyer Andréa E. Tijhuis Diana C. J. Spierings Michael Schubert Silvia Taglietti Chiara Soriani Simon Gemble Renata Basto Nick Rhind Floris Foijer Uri Ben-David Daniele Fachinetti Ylli Doksani Stefano Santaguida Short-term molecular consequences of chromosome mis-segregation for genome stability Nature Communications |
| title | Short-term molecular consequences of chromosome mis-segregation for genome stability |
| title_full | Short-term molecular consequences of chromosome mis-segregation for genome stability |
| title_fullStr | Short-term molecular consequences of chromosome mis-segregation for genome stability |
| title_full_unstemmed | Short-term molecular consequences of chromosome mis-segregation for genome stability |
| title_short | Short-term molecular consequences of chromosome mis-segregation for genome stability |
| title_sort | short term molecular consequences of chromosome mis segregation for genome stability |
| url | https://doi.org/10.1038/s41467-023-37095-7 |
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