Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal

Abstract Objective Diabetes mellitus is a common metabolic disorder throughout the world which can negatively affect the function of various body organs. Due to their availability and few side effects, herbal medicines have been proposed as suitable alternatives in the management of diabetes. Previo...

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Main Authors: Nasibeh Roozbeh, Leili Darvish, Fatemeh Abdi
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Research Notes
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13104-017-2646-1
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author Nasibeh Roozbeh
Leili Darvish
Fatemeh Abdi
author_facet Nasibeh Roozbeh
Leili Darvish
Fatemeh Abdi
author_sort Nasibeh Roozbeh
collection DOAJ
description Abstract Objective Diabetes mellitus is a common metabolic disorder throughout the world which can negatively affect the function of various body organs. Due to their availability and few side effects, herbal medicines have been proposed as suitable alternatives in the management of diabetes. Previous studies have confirmed the anti diabetic properties of Acacia nilotica. The hypoglycemic effects of this plant have been attributed to its role in stimulating the islets of Langerhans to produce more insulin. The present paper describes a systematic review protocol for the assessment of the hypoglycemic effects of A. nilotica. Main texts Randomized and non-randomized placebo-controlled clinical trials, performed during 1999–2016 will be included. The outcomes will be measured through FBS, GCT, GTT, and OGTT in all of studies and in addition to these tests, will be measured 2HPP and HbA1c level in human study. Well-known databases will be searched for selected key terms A. nilotica, type II diabetes and hypoglycemia. The quality assessment of the selected papers will be evaluated based on SYRCLE and Cochrane Risk of Bias Tool. We believe that our findings will provide details about difficulties researchers face during the design of protocols or implementation of scientific studies. Ultimately, the publication of our findings will facilitate the development of effective treatment strategies to promote the health of people with type II DM. PROSPERO registration CRD42016053141
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spelling doaj.art-e2284f5ef25948cebd95e9625c76686b2022-12-21T19:37:54ZengBMCBMC Research Notes1756-05002017-07-011011510.1186/s13104-017-2646-1Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposalNasibeh Roozbeh0Leili Darvish1Fatemeh Abdi2Mother and Child Welfare Research Center, Hormozgan University of Medical SciencesMother and Child Welfare Research Center, Hormozgan University of Medical SciencesStudents Research Committee, Nursing and Midwifery Faculty, Shahid Beheshti University of Medical SciencesAbstract Objective Diabetes mellitus is a common metabolic disorder throughout the world which can negatively affect the function of various body organs. Due to their availability and few side effects, herbal medicines have been proposed as suitable alternatives in the management of diabetes. Previous studies have confirmed the anti diabetic properties of Acacia nilotica. The hypoglycemic effects of this plant have been attributed to its role in stimulating the islets of Langerhans to produce more insulin. The present paper describes a systematic review protocol for the assessment of the hypoglycemic effects of A. nilotica. Main texts Randomized and non-randomized placebo-controlled clinical trials, performed during 1999–2016 will be included. The outcomes will be measured through FBS, GCT, GTT, and OGTT in all of studies and in addition to these tests, will be measured 2HPP and HbA1c level in human study. Well-known databases will be searched for selected key terms A. nilotica, type II diabetes and hypoglycemia. The quality assessment of the selected papers will be evaluated based on SYRCLE and Cochrane Risk of Bias Tool. We believe that our findings will provide details about difficulties researchers face during the design of protocols or implementation of scientific studies. Ultimately, the publication of our findings will facilitate the development of effective treatment strategies to promote the health of people with type II DM. PROSPERO registration CRD42016053141http://link.springer.com/article/10.1186/s13104-017-2646-1HypoglycemiaAcacia NiloticaDiabetesII
spellingShingle Nasibeh Roozbeh
Leili Darvish
Fatemeh Abdi
Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal
BMC Research Notes
Hypoglycemia
Acacia Nilotica
DiabetesII
title Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal
title_full Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal
title_fullStr Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal
title_full_unstemmed Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal
title_short Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal
title_sort hypoglycemic effects of acacia nilotica in type ii diabetes a research proposal
topic Hypoglycemia
Acacia Nilotica
DiabetesII
url http://link.springer.com/article/10.1186/s13104-017-2646-1
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AT leilidarvish hypoglycemiceffectsofacacianiloticaintypeiidiabetesaresearchproposal
AT fatemehabdi hypoglycemiceffectsofacacianiloticaintypeiidiabetesaresearchproposal