Expression and Function of Toll Pathway Components in the Early Development of the Wasp <i>Nasonia vitripennis</i>
The Toll signaling pathway is the main source of embryonic DV polarity in the fly <i>Drosophila melanogaster.</i> This pathway appears to have been co-opted from an ancestral innate immunity system within the insects and has been deployed in different ways among insect taxa. Here we repo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Journal of Developmental Biology |
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| Online Access: | https://www.mdpi.com/2221-3759/10/1/7 |
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| author | Daniel Pers Thomas Buchta Orhan Özüak Siegfried Roth Jeremy A. Lynch |
| author_facet | Daniel Pers Thomas Buchta Orhan Özüak Siegfried Roth Jeremy A. Lynch |
| author_sort | Daniel Pers |
| collection | DOAJ |
| description | The Toll signaling pathway is the main source of embryonic DV polarity in the fly <i>Drosophila melanogaster.</i> This pathway appears to have been co-opted from an ancestral innate immunity system within the insects and has been deployed in different ways among insect taxa. Here we report the expression and function of homologs of the important components of the <i>D. melanogaster</i> Toll pathway in the wasp <i>Nasonia vitripennis.</i> We found homologs for all the components; many components had one or more additional paralogs in the wasp relative the fly. We also found significant deviations in expression patterns of <i>N. vitripennis</i> homologs. Finally, we provide some preliminary functional analyses of the <i>N. vitripennis</i> homologs, where we find a mixture of conservation and divergence of function. |
| first_indexed | 2024-03-09T19:37:00Z |
| format | Article |
| id | doaj.art-e22c510280f44db6bd27d9149bb46dec |
| institution | Directory Open Access Journal |
| issn | 2221-3759 |
| language | English |
| last_indexed | 2024-03-09T19:37:00Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Developmental Biology |
| spelling | doaj.art-e22c510280f44db6bd27d9149bb46dec2023-11-24T01:53:03ZengMDPI AGJournal of Developmental Biology2221-37592022-01-01101710.3390/jdb10010007Expression and Function of Toll Pathway Components in the Early Development of the Wasp <i>Nasonia vitripennis</i>Daniel Pers0Thomas Buchta1Orhan Özüak2Siegfried Roth3Jeremy A. Lynch4Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USADepartment of Developmental Biology, University of Cologne, 50674 Cologne, GermanyDepartment of Developmental Biology, University of Cologne, 50674 Cologne, GermanyDepartment of Developmental Biology, University of Cologne, 50674 Cologne, GermanyDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USAThe Toll signaling pathway is the main source of embryonic DV polarity in the fly <i>Drosophila melanogaster.</i> This pathway appears to have been co-opted from an ancestral innate immunity system within the insects and has been deployed in different ways among insect taxa. Here we report the expression and function of homologs of the important components of the <i>D. melanogaster</i> Toll pathway in the wasp <i>Nasonia vitripennis.</i> We found homologs for all the components; many components had one or more additional paralogs in the wasp relative the fly. We also found significant deviations in expression patterns of <i>N. vitripennis</i> homologs. Finally, we provide some preliminary functional analyses of the <i>N. vitripennis</i> homologs, where we find a mixture of conservation and divergence of function.https://www.mdpi.com/2221-3759/10/1/7<i>Nasonia</i>tollembryonic patterningdorsal-ventral |
| spellingShingle | Daniel Pers Thomas Buchta Orhan Özüak Siegfried Roth Jeremy A. Lynch Expression and Function of Toll Pathway Components in the Early Development of the Wasp <i>Nasonia vitripennis</i> Journal of Developmental Biology <i>Nasonia</i> toll embryonic patterning dorsal-ventral |
| title | Expression and Function of Toll Pathway Components in the Early Development of the Wasp <i>Nasonia vitripennis</i> |
| title_full | Expression and Function of Toll Pathway Components in the Early Development of the Wasp <i>Nasonia vitripennis</i> |
| title_fullStr | Expression and Function of Toll Pathway Components in the Early Development of the Wasp <i>Nasonia vitripennis</i> |
| title_full_unstemmed | Expression and Function of Toll Pathway Components in the Early Development of the Wasp <i>Nasonia vitripennis</i> |
| title_short | Expression and Function of Toll Pathway Components in the Early Development of the Wasp <i>Nasonia vitripennis</i> |
| title_sort | expression and function of toll pathway components in the early development of the wasp i nasonia vitripennis i |
| topic | <i>Nasonia</i> toll embryonic patterning dorsal-ventral |
| url | https://www.mdpi.com/2221-3759/10/1/7 |
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