Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease
<b>Objective:</b> Incidence of renal cell carcinoma (RCC) in patients with end-stage renal disease (ESRD) is higher than in the general population. It is difficult to detect RCC in ESRD kidney using routine gray scaled ultrasonography (USG). The resistive...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Society of Ultrasound in Medicine
2014-04-01
|
| Series: | Ultrasonography |
| Subjects: | |
| Online Access: | http://e-ultrasonography.org/upload/usg-14001.pdf |
| _version_ | 1818806027252924416 |
|---|---|
| author | Sang Youn Kim Sungmin Woo Sung Il Hwang Min Hoan Moon Chang Kyu Sung Hak Jong Lee Jeong Yeon Cho Seung Hyup Kim |
| author_facet | Sang Youn Kim Sungmin Woo Sung Il Hwang Min Hoan Moon Chang Kyu Sung Hak Jong Lee Jeong Yeon Cho Seung Hyup Kim |
| author_sort | Sang Youn Kim |
| collection | DOAJ |
| description | <b>Objective:</b> Incidence of renal cell carcinoma (RCC) in patients with end-stage renal disease (ESRD) is higher than in the general population. It is difficult to detect RCC in ESRD kidney using routine gray scaled ultrasonography (USG). The resistive index (RI) measured in the intra-tumor artery of RCC can be expected to be lower than the background parenchyma of the ESRD kidney due to their disorganized neovascularization. This study explored the usefulness of RI on spectral Doppler USG for detection of RCC in ESRD kidney. Materials and Methods: We identified 17 patients with ESRD kidneys in which renal masses were suspected on routine USG. They performed CT scans and additional Doppler USG for characterization of detected lesions. All underwent radical nephrectomy with the suspicion of RCC. 14 patients finally were included. RI measurements were done at the region of suspected renal mass and backgreround renal parenchyma. The intraclass correlation coefficient (ICC) was used to assess the reproducibility of RI measurement. The paired t-test was used to compare the RI values between the renal mass and background renal parenchyma (P < 0.05). Results: RI values measured at RCCs were significantly lower than those measured at background renal parenchymae (0.41~0.65 vs. 0.75~0.89) (P < 0.001). The intra-reader reproducibility proved to be excellent and good for the renal masses and parenchymae, respectively (P<0.001).
Conclusion: RI on spectral Doppler ultrasonography is useful in detecting RCC in patients with ESRD. RI values measured at RCCs were significantly lower than those measured at background renal parenchymae. |
| first_indexed | 2024-12-18T19:03:14Z |
| format | Article |
| id | doaj.art-e22ecb0398014b05982dcd08af8a25da |
| institution | Directory Open Access Journal |
| issn | 2288-5919 |
| language | English |
| last_indexed | 2024-12-18T19:03:14Z |
| publishDate | 2014-04-01 |
| publisher | Korean Society of Ultrasound in Medicine |
| record_format | Article |
| series | Ultrasonography |
| spelling | doaj.art-e22ecb0398014b05982dcd08af8a25da2022-12-21T20:56:28ZengKorean Society of Ultrasound in MedicineUltrasonography2288-59192014-04-0133213614210.14366/usg.1400132Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal diseaseSang Youn Kim0Sungmin Woo1Sung Il Hwang2Min Hoan Moon3Chang Kyu Sung4Hak Jong Lee5Jeong Yeon Cho6Seung Hyup Kim7Department of Radiology, Seoul National University Hospital, Seoul, KoreaDepartment of Radiology, Seoul National University Hospital, Seoul, KoreaDepartment of Radiology, Seoul National University Bundang Hospital, Seongnam, KoreaDepartment of Radiology, Seoul National University Boramae Hospital, Seoul, KoreaDepartment of Radiology, Seoul National University Boramae Hospital, Seoul, KoreaDepartment of Radiology, Seoul National University Bundang Hospital, Seongnam, KoreaDepartment of Radiology, Seoul National University Hospital, Seoul, KoreaDepartment of Radiology, Seoul National University Hospital, Seoul, Korea<b>Objective:</b> Incidence of renal cell carcinoma (RCC) in patients with end-stage renal disease (ESRD) is higher than in the general population. It is difficult to detect RCC in ESRD kidney using routine gray scaled ultrasonography (USG). The resistive index (RI) measured in the intra-tumor artery of RCC can be expected to be lower than the background parenchyma of the ESRD kidney due to their disorganized neovascularization. This study explored the usefulness of RI on spectral Doppler USG for detection of RCC in ESRD kidney. Materials and Methods: We identified 17 patients with ESRD kidneys in which renal masses were suspected on routine USG. They performed CT scans and additional Doppler USG for characterization of detected lesions. All underwent radical nephrectomy with the suspicion of RCC. 14 patients finally were included. RI measurements were done at the region of suspected renal mass and backgreround renal parenchyma. The intraclass correlation coefficient (ICC) was used to assess the reproducibility of RI measurement. The paired t-test was used to compare the RI values between the renal mass and background renal parenchyma (P < 0.05). Results: RI values measured at RCCs were significantly lower than those measured at background renal parenchymae (0.41~0.65 vs. 0.75~0.89) (P < 0.001). The intra-reader reproducibility proved to be excellent and good for the renal masses and parenchymae, respectively (P<0.001). Conclusion: RI on spectral Doppler ultrasonography is useful in detecting RCC in patients with ESRD. RI values measured at RCCs were significantly lower than those measured at background renal parenchymae.http://e-ultrasonography.org/upload/usg-14001.pdfUltrasonography, Doppler, Pulsed Ultrasonography, Doppler, Color Kidney Failure, Chronic Carcinoma, Renal Cell Resistive Index |
| spellingShingle | Sang Youn Kim Sungmin Woo Sung Il Hwang Min Hoan Moon Chang Kyu Sung Hak Jong Lee Jeong Yeon Cho Seung Hyup Kim Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease Ultrasonography Ultrasonography, Doppler, Pulsed Ultrasonography, Doppler, Color Kidney Failure, Chronic Carcinoma, Renal Cell Resistive Index |
| title | Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease |
| title_full | Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease |
| title_fullStr | Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease |
| title_full_unstemmed | Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease |
| title_short | Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease |
| title_sort | usefulness of resistive index on spectral doppler ultrasonography in the detection of renal cell carcinoma in patients with end stage renal disease |
| topic | Ultrasonography, Doppler, Pulsed Ultrasonography, Doppler, Color Kidney Failure, Chronic Carcinoma, Renal Cell Resistive Index |
| url | http://e-ultrasonography.org/upload/usg-14001.pdf |
| work_keys_str_mv | AT sangyounkim usefulnessofresistiveindexonspectraldopplerultrasonographyinthedetectionofrenalcellcarcinomainpatientswithendstagerenaldisease AT sungminwoo usefulnessofresistiveindexonspectraldopplerultrasonographyinthedetectionofrenalcellcarcinomainpatientswithendstagerenaldisease AT sungilhwang usefulnessofresistiveindexonspectraldopplerultrasonographyinthedetectionofrenalcellcarcinomainpatientswithendstagerenaldisease AT minhoanmoon usefulnessofresistiveindexonspectraldopplerultrasonographyinthedetectionofrenalcellcarcinomainpatientswithendstagerenaldisease AT changkyusung usefulnessofresistiveindexonspectraldopplerultrasonographyinthedetectionofrenalcellcarcinomainpatientswithendstagerenaldisease AT hakjonglee usefulnessofresistiveindexonspectraldopplerultrasonographyinthedetectionofrenalcellcarcinomainpatientswithendstagerenaldisease AT jeongyeoncho usefulnessofresistiveindexonspectraldopplerultrasonographyinthedetectionofrenalcellcarcinomainpatientswithendstagerenaldisease AT seunghyupkim usefulnessofresistiveindexonspectraldopplerultrasonographyinthedetectionofrenalcellcarcinomainpatientswithendstagerenaldisease |