Seropositivity to Cysticercosis in School-Age Children Living in a Low-Income Municipality in the Midwest Region of Brazil
Background: Human cysticercosis (CC) is a global public health problem, especially in Latin America, including Brazil. We aimed to analyze the seroprevalence of CC among school-age children and adolescents. Methods: We analyzed the presence of specific IgG antibodies against Taenia solium metace...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-06-01
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| Series: | Iranian Journal of Parasitology |
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| Online Access: | https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3511 |
| _version_ | 1797742560862535680 |
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| author | Dayane Moraes Émelin Alves dos Santos José Antônio Alves Mendes Ivanildes Solange da Costa Barcelos João Batista Alves de Souza Maria do Rosário de Fátima Gonçalves-Pires Julia Maria Costa-Cruz Rosângela Maria Rodrigues |
| author_facet | Dayane Moraes Émelin Alves dos Santos José Antônio Alves Mendes Ivanildes Solange da Costa Barcelos João Batista Alves de Souza Maria do Rosário de Fátima Gonçalves-Pires Julia Maria Costa-Cruz Rosângela Maria Rodrigues |
| author_sort | Dayane Moraes |
| collection | DOAJ |
| description |
Background: Human cysticercosis (CC) is a global public health problem, especially in Latin America, including Brazil. We aimed to analyze the seroprevalence of CC among school-age children and adolescents.
Methods: We analyzed the presence of specific IgG antibodies against Taenia solium metacestodes in 500 serum samples from elementary school children and adolescents in Jataí City, state of Goiás, Brazil. IgG antibodies against the antigenic extract of the parasite were detected and analyzed by ELISA, and specific peptides were identified by confirmatory Western Blotting test.
Results: Of the 500 study participants, 205 (41%) were male, and 295 (59%) were female. Participants aged between 4 and 18 years (mean age 8.4 years). The percentage of serum samples reactive by ELISA was 37.2%. These samples were analyzed by Western Blotting, which confirmed that the seropositivity rate was 6.2% (95% CI 2.4–14.7) in 31 samples reactive for CC-specific bands, determined in serum samples from 18 male (5–11 years old) and 13 female (4–12 years old) students.
Conclusion: The CC seroprevalence demonstrated in schoolchildren suggests that this parasitosis is endemic in the study area. Further investigations are necessary to clarify the local epidemiology of this parasitosis.
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| first_indexed | 2024-03-12T14:42:27Z |
| format | Article |
| id | doaj.art-e2316a248c09416984c5f5f570864a7d |
| institution | Directory Open Access Journal |
| issn | 1735-7020 2008-238X |
| language | English |
| last_indexed | 2024-03-12T14:42:27Z |
| publishDate | 2023-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Parasitology |
| spelling | doaj.art-e2316a248c09416984c5f5f570864a7d2023-08-16T06:06:31ZengTehran University of Medical SciencesIranian Journal of Parasitology1735-70202008-238X2023-06-0118210.18502/ijpa.v18i2.13187Seropositivity to Cysticercosis in School-Age Children Living in a Low-Income Municipality in the Midwest Region of BrazilDayane Moraes0Émelin Alves dos Santos1José Antônio Alves Mendes2Ivanildes Solange da Costa Barcelos3João Batista Alves de Souza4Maria do Rosário de Fátima Gonçalves-Pires5Julia Maria Costa-Cruz6Rosângela Maria Rodrigues7Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, BrazilParasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, BrazilParasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, BrazilImmunology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, BrazilParasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, BrazilParasitic Diagnosis Laboratory, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Mi-nas Gerais State, BrazilParasitic Diagnosis Laboratory, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Mi-nas Gerais State, BrazilParasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil Background: Human cysticercosis (CC) is a global public health problem, especially in Latin America, including Brazil. We aimed to analyze the seroprevalence of CC among school-age children and adolescents. Methods: We analyzed the presence of specific IgG antibodies against Taenia solium metacestodes in 500 serum samples from elementary school children and adolescents in Jataí City, state of Goiás, Brazil. IgG antibodies against the antigenic extract of the parasite were detected and analyzed by ELISA, and specific peptides were identified by confirmatory Western Blotting test. Results: Of the 500 study participants, 205 (41%) were male, and 295 (59%) were female. Participants aged between 4 and 18 years (mean age 8.4 years). The percentage of serum samples reactive by ELISA was 37.2%. These samples were analyzed by Western Blotting, which confirmed that the seropositivity rate was 6.2% (95% CI 2.4–14.7) in 31 samples reactive for CC-specific bands, determined in serum samples from 18 male (5–11 years old) and 13 female (4–12 years old) students. Conclusion: The CC seroprevalence demonstrated in schoolchildren suggests that this parasitosis is endemic in the study area. Further investigations are necessary to clarify the local epidemiology of this parasitosis. https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3511CysticercosisChild healthStudentsSeroprevalenceBrazil |
| spellingShingle | Dayane Moraes Émelin Alves dos Santos José Antônio Alves Mendes Ivanildes Solange da Costa Barcelos João Batista Alves de Souza Maria do Rosário de Fátima Gonçalves-Pires Julia Maria Costa-Cruz Rosângela Maria Rodrigues Seropositivity to Cysticercosis in School-Age Children Living in a Low-Income Municipality in the Midwest Region of Brazil Iranian Journal of Parasitology Cysticercosis Child health Students Seroprevalence Brazil |
| title | Seropositivity to Cysticercosis in School-Age Children Living in a Low-Income Municipality in the Midwest Region of Brazil |
| title_full | Seropositivity to Cysticercosis in School-Age Children Living in a Low-Income Municipality in the Midwest Region of Brazil |
| title_fullStr | Seropositivity to Cysticercosis in School-Age Children Living in a Low-Income Municipality in the Midwest Region of Brazil |
| title_full_unstemmed | Seropositivity to Cysticercosis in School-Age Children Living in a Low-Income Municipality in the Midwest Region of Brazil |
| title_short | Seropositivity to Cysticercosis in School-Age Children Living in a Low-Income Municipality in the Midwest Region of Brazil |
| title_sort | seropositivity to cysticercosis in school age children living in a low income municipality in the midwest region of brazil |
| topic | Cysticercosis Child health Students Seroprevalence Brazil |
| url | https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3511 |
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