Detection of norovirus and rotavirus among inpatients with acute gastroenteritis in a medical center in northern Taiwan, 2013–2018
Background: Norovirus (NoV) and rotavirus (RV) are among the most common causes of acute gastroenteritis (AGE) of all ages worldwide. There have been scanty reports of the epidemiology data of NoV AGE from clinical virologic laboratory. Methods: All stool specimens sent to the virologic laboratory i...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-12-01
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| Series: | Journal of Microbiology, Immunology and Infection |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1684118220301572 |
| _version_ | 1818725038548844544 |
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| author | Cha-Shien Yen Yhu-Chering Huang Chih-Jung Chen Shian-Sen Shie Shu-Li Yang Chung-Guei Huang Kuo-Chien Tsao Cheng-Hsun Chiu Yu-Chia Hsieh Chen-Yen Kuo Kuan-Ying Arthur Huang Tzou-Yien Lin |
| author_facet | Cha-Shien Yen Yhu-Chering Huang Chih-Jung Chen Shian-Sen Shie Shu-Li Yang Chung-Guei Huang Kuo-Chien Tsao Cheng-Hsun Chiu Yu-Chia Hsieh Chen-Yen Kuo Kuan-Ying Arthur Huang Tzou-Yien Lin |
| author_sort | Cha-Shien Yen |
| collection | DOAJ |
| description | Background: Norovirus (NoV) and rotavirus (RV) are among the most common causes of acute gastroenteritis (AGE) of all ages worldwide. There have been scanty reports of the epidemiology data of NoV AGE from clinical virologic laboratory. Methods: All stool specimens sent to the virologic laboratory in a medical center in Taiwan for detection of both NoV (by reverse transcription-polymerase chain reaction) and RV (by enzyme immunoassay) from 2013 to 2018 were included for analysis. Results: A total of 15,991 specimens, annually ranging from 2430 in 2017–2915 in 2013, were included. 48.0% and 73.1% of the specimens were obtained from children aged < two years and < five years, respectively. Overall, the positive rate was 13.8% for NoV and 13.2% for RV. Yearly positive rate of NoV ranged from 11.1% to 17.4%. The positive rate in 2018 (17.4%) was significantly higher than that in other study years. NoV positive rate was higher in cold season from January (28.3%), February (23.1%), to March (17.9%) while lower in warm seasons from May to September (less than 10%). By age, NoV positive rate was highest in aged 1–4 years (17.3%) and decreased with age. The yearly positive rate of RV showed a significantly steady decrease from 15.6% in 2013 to 9.1% in 2018 (p < 0.001 by trend analysis). Conclusions: In northern Taiwan, NoV, surpassing RV, accounted for one of seven inpatients with AGE during 2013–2018. NoV activity peaked in cold season and children aged <5 years were more commonly encountered. |
| first_indexed | 2024-12-17T21:35:57Z |
| format | Article |
| id | doaj.art-e231d7bea1944443a6c748ea2075a9a6 |
| institution | Directory Open Access Journal |
| issn | 1684-1182 |
| language | English |
| last_indexed | 2024-12-17T21:35:57Z |
| publishDate | 2020-12-01 |
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| series | Journal of Microbiology, Immunology and Infection |
| spelling | doaj.art-e231d7bea1944443a6c748ea2075a9a62022-12-21T21:31:45ZengElsevierJournal of Microbiology, Immunology and Infection1684-11822020-12-01536955962Detection of norovirus and rotavirus among inpatients with acute gastroenteritis in a medical center in northern Taiwan, 2013–2018Cha-Shien Yen0Yhu-Chering Huang1Chih-Jung Chen2Shian-Sen Shie3Shu-Li Yang4Chung-Guei Huang5Kuo-Chien Tsao6Cheng-Hsun Chiu7Yu-Chia Hsieh8Chen-Yen Kuo9Kuan-Ying Arthur Huang10Tzou-Yien Lin11Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, Taiwan; Corresponding author. Division of Pediatric Infectious diseases, Department of Pediatrics, Chang Gung Memorial Hospital, No. 5, Fu-Shin Street, Kweishan 333, Taoyuan, Taiwan. Fax: +886 3 3288957.Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, TaiwanDivision of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Laboratory Medicine, Chang Gung Memorial Hospital, Taoyuan, TaiwanDepartment of Laboratory Medicine, Chang Gung Memorial Hospital, Taoyuan, TaiwanDepartment of Laboratory Medicine, Chang Gung Memorial Hospital, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, TaiwanBackground: Norovirus (NoV) and rotavirus (RV) are among the most common causes of acute gastroenteritis (AGE) of all ages worldwide. There have been scanty reports of the epidemiology data of NoV AGE from clinical virologic laboratory. Methods: All stool specimens sent to the virologic laboratory in a medical center in Taiwan for detection of both NoV (by reverse transcription-polymerase chain reaction) and RV (by enzyme immunoassay) from 2013 to 2018 were included for analysis. Results: A total of 15,991 specimens, annually ranging from 2430 in 2017–2915 in 2013, were included. 48.0% and 73.1% of the specimens were obtained from children aged < two years and < five years, respectively. Overall, the positive rate was 13.8% for NoV and 13.2% for RV. Yearly positive rate of NoV ranged from 11.1% to 17.4%. The positive rate in 2018 (17.4%) was significantly higher than that in other study years. NoV positive rate was higher in cold season from January (28.3%), February (23.1%), to March (17.9%) while lower in warm seasons from May to September (less than 10%). By age, NoV positive rate was highest in aged 1–4 years (17.3%) and decreased with age. The yearly positive rate of RV showed a significantly steady decrease from 15.6% in 2013 to 9.1% in 2018 (p < 0.001 by trend analysis). Conclusions: In northern Taiwan, NoV, surpassing RV, accounted for one of seven inpatients with AGE during 2013–2018. NoV activity peaked in cold season and children aged <5 years were more commonly encountered.http://www.sciencedirect.com/science/article/pii/S1684118220301572NorovirusRotavirusRotavirus vaccineEpidemiologyTaiwan |
| spellingShingle | Cha-Shien Yen Yhu-Chering Huang Chih-Jung Chen Shian-Sen Shie Shu-Li Yang Chung-Guei Huang Kuo-Chien Tsao Cheng-Hsun Chiu Yu-Chia Hsieh Chen-Yen Kuo Kuan-Ying Arthur Huang Tzou-Yien Lin Detection of norovirus and rotavirus among inpatients with acute gastroenteritis in a medical center in northern Taiwan, 2013–2018 Journal of Microbiology, Immunology and Infection Norovirus Rotavirus Rotavirus vaccine Epidemiology Taiwan |
| title | Detection of norovirus and rotavirus among inpatients with acute gastroenteritis in a medical center in northern Taiwan, 2013–2018 |
| title_full | Detection of norovirus and rotavirus among inpatients with acute gastroenteritis in a medical center in northern Taiwan, 2013–2018 |
| title_fullStr | Detection of norovirus and rotavirus among inpatients with acute gastroenteritis in a medical center in northern Taiwan, 2013–2018 |
| title_full_unstemmed | Detection of norovirus and rotavirus among inpatients with acute gastroenteritis in a medical center in northern Taiwan, 2013–2018 |
| title_short | Detection of norovirus and rotavirus among inpatients with acute gastroenteritis in a medical center in northern Taiwan, 2013–2018 |
| title_sort | detection of norovirus and rotavirus among inpatients with acute gastroenteritis in a medical center in northern taiwan 2013 2018 |
| topic | Norovirus Rotavirus Rotavirus vaccine Epidemiology Taiwan |
| url | http://www.sciencedirect.com/science/article/pii/S1684118220301572 |
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