Secretome effect of adipose tissue-derived stem cells cultured two-dimensionally and three-dimensionally in mice with streptozocin induced type 1 diabetes

Secretome effect of adipose tissue-derived stem cells cultured two-dimensionally and three-dimensionally in mice with streptozocin induced type 1 diabetes

Aims: To analyze therapeutic potential of the conditioned medium from adipose tissue-derived stem cells (ASC) cultivated in 2D (CM-2D) and 3D (CM-3D) models, in mice with Type 1 diabetes (T1D) induced by streptozotocin. Main methods: Viability andCD105 expression of 2D and 3D ASC were analyzed by fl...

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Bibliographic Details
Main Authors: Isabelle Dias, Daphne Pinheiro, Karina Ribeiro Silva, Ana Carolina Stumbo, Alessandra Thole, Erika Cortez, Laís de Carvalho, Simone Nunes Carvalho
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Pharmacology and Drug Discovery
Subjects:
Diabetes type 1
Adipose stem cells
Secretome
3D cell culture
Online Access:http://www.sciencedirect.com/science/article/pii/S2590257121000560

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