Changes in Arterial Stiffness in Response to Blood Flow Restriction Resistance Training: A Narrative Review
Arterial stiffness naturally increases with age and is a known predictor of cardiovascular morbimortality. Blood flow restriction (BFR) training involves decreasing muscle blood flow by applying a strap or a pneumatic cuff during exercise. BFR induces muscle hypertrophy even at low intensities, maki...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-12-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/12/24/7602 |
| _version_ | 1797380576880099328 |
|---|---|
| author | Ioana Mădălina Zota Cristina Mihaela Ghiciuc Doina Clementina Cojocaru Corina Lucia Dima-Cozma Maria Magdalena Leon Radu Sebastian Gavril Mihai Roca Alexandru Dan Costache Alexandra Maștaleru Larisa Anghel Cristian Stătescu Radu Andy Sascău Florin Mitu |
| author_facet | Ioana Mădălina Zota Cristina Mihaela Ghiciuc Doina Clementina Cojocaru Corina Lucia Dima-Cozma Maria Magdalena Leon Radu Sebastian Gavril Mihai Roca Alexandru Dan Costache Alexandra Maștaleru Larisa Anghel Cristian Stătescu Radu Andy Sascău Florin Mitu |
| author_sort | Ioana Mădălina Zota |
| collection | DOAJ |
| description | Arterial stiffness naturally increases with age and is a known predictor of cardiovascular morbimortality. Blood flow restriction (BFR) training involves decreasing muscle blood flow by applying a strap or a pneumatic cuff during exercise. BFR induces muscle hypertrophy even at low intensities, making it an appealing option for older, untrained individuals. However, BFR use in patients with cardiovascular comorbidities is limited by the increased pressor and chronotropic response observed in hypertensive elderly patients. Furthermore, the impact of BFR on vascular function remains unclear. We conducted a comprehensive literature review according to PRISMA guidelines, summarizing available data on the acute and long-term consequences of BFR training on vascular function. Although evidence is still scarce, it seems that BFR has a mild or neutral long-term impact on arterial stiffness. However, current research shows that BFR can cause an abrupt, albeit transient, increase in PWV and central blood pressure. BFR and, preferably, lower-body BFR, should be prescribed with caution in older populations, especially in hypertensive patients who have an exacerbated muscle metaboreflex pressor response. Longer follow-up studies are required to assess the chronic effect of BFR training on arterial stiffness, especially in elderly patients who are usually unable to tolerate high-intensity resistance exercises. |
| first_indexed | 2024-03-08T20:39:19Z |
| format | Article |
| id | doaj.art-e2383910aabb46d6ac6eeefbc3a271eb |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-08T20:39:19Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-e2383910aabb46d6ac6eeefbc3a271eb2023-12-22T14:17:08ZengMDPI AGJournal of Clinical Medicine2077-03832023-12-011224760210.3390/jcm12247602Changes in Arterial Stiffness in Response to Blood Flow Restriction Resistance Training: A Narrative ReviewIoana Mădălina Zota0Cristina Mihaela Ghiciuc1Doina Clementina Cojocaru2Corina Lucia Dima-Cozma3Maria Magdalena Leon4Radu Sebastian Gavril5Mihai Roca6Alexandru Dan Costache7Alexandra Maștaleru8Larisa Anghel9Cristian Stătescu10Radu Andy Sascău11Florin Mitu12Department of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaPharmacology, Clinical Pharmacology and Algeziology, Department of Morpho-Functional Sciences II, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaDepartment of Medical Specialties I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700111 Iași, RomaniaArterial stiffness naturally increases with age and is a known predictor of cardiovascular morbimortality. Blood flow restriction (BFR) training involves decreasing muscle blood flow by applying a strap or a pneumatic cuff during exercise. BFR induces muscle hypertrophy even at low intensities, making it an appealing option for older, untrained individuals. However, BFR use in patients with cardiovascular comorbidities is limited by the increased pressor and chronotropic response observed in hypertensive elderly patients. Furthermore, the impact of BFR on vascular function remains unclear. We conducted a comprehensive literature review according to PRISMA guidelines, summarizing available data on the acute and long-term consequences of BFR training on vascular function. Although evidence is still scarce, it seems that BFR has a mild or neutral long-term impact on arterial stiffness. However, current research shows that BFR can cause an abrupt, albeit transient, increase in PWV and central blood pressure. BFR and, preferably, lower-body BFR, should be prescribed with caution in older populations, especially in hypertensive patients who have an exacerbated muscle metaboreflex pressor response. Longer follow-up studies are required to assess the chronic effect of BFR training on arterial stiffness, especially in elderly patients who are usually unable to tolerate high-intensity resistance exercises.https://www.mdpi.com/2077-0383/12/24/7602blood flow restriction trainingvascular stiffnesspulse wave velocityvascular agingresistance training |
| spellingShingle | Ioana Mădălina Zota Cristina Mihaela Ghiciuc Doina Clementina Cojocaru Corina Lucia Dima-Cozma Maria Magdalena Leon Radu Sebastian Gavril Mihai Roca Alexandru Dan Costache Alexandra Maștaleru Larisa Anghel Cristian Stătescu Radu Andy Sascău Florin Mitu Changes in Arterial Stiffness in Response to Blood Flow Restriction Resistance Training: A Narrative Review Journal of Clinical Medicine blood flow restriction training vascular stiffness pulse wave velocity vascular aging resistance training |
| title | Changes in Arterial Stiffness in Response to Blood Flow Restriction Resistance Training: A Narrative Review |
| title_full | Changes in Arterial Stiffness in Response to Blood Flow Restriction Resistance Training: A Narrative Review |
| title_fullStr | Changes in Arterial Stiffness in Response to Blood Flow Restriction Resistance Training: A Narrative Review |
| title_full_unstemmed | Changes in Arterial Stiffness in Response to Blood Flow Restriction Resistance Training: A Narrative Review |
| title_short | Changes in Arterial Stiffness in Response to Blood Flow Restriction Resistance Training: A Narrative Review |
| title_sort | changes in arterial stiffness in response to blood flow restriction resistance training a narrative review |
| topic | blood flow restriction training vascular stiffness pulse wave velocity vascular aging resistance training |
| url | https://www.mdpi.com/2077-0383/12/24/7602 |
| work_keys_str_mv | AT ioanamadalinazota changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT cristinamihaelaghiciuc changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT doinaclementinacojocaru changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT corinaluciadimacozma changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT mariamagdalenaleon changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT radusebastiangavril changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT mihairoca changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT alexandrudancostache changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT alexandramastaleru changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT larisaanghel changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT cristianstatescu changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT raduandysascau changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview AT florinmitu changesinarterialstiffnessinresponsetobloodflowrestrictionresistancetraininganarrativereview |