Protocol for the Ketamine for Postoperative Avoidance of Depressive Symptoms (K-PASS) feasibility study: A randomized clinical trial [version 1; peer review: 2 approved]

Protocol for the Ketamine for Postoperative Avoidance of Depressive Symptoms (K-PASS) feasibility study: A randomized clinical trial [version 1; peer review: 2 approved]

Background: Postoperative depressive symptoms are associated with pain, readmissions, death, and other undesirable outcomes. Ketamine produces rapid but transient antidepressant effects in the perioperative setting. Longer infusions confer lasting antidepressant activity in patients with treatment-r...

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Bibliographic Details
Main Authors: Jon T. Willie, Nuri B. Farber, Ben J.A. Palanca, Julie A. Schweiger, Bradley A. Fritz, Bethany R. Tellor Pennington
Format: Article
Language:English
Published: F1000 Research Ltd 2022-05-01
Series:F1000Research
Subjects:
Depression
Feasibility
Ketamine
Protocol
Randomized Clinical Trial
Surgery
eng
Online Access:https://f1000research.com/articles/11-510/v1

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