Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans

Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans

Abstract Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis. Synchronized L4 stage C. elegans were treated with 7% isoflurane f...

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Bibliographic Details
Main Authors: Tao Zhang, Cheng Ni, Cheng Li, Pan Lu, Dan Chen, Yuanlin Dong, Johnathan R. Whetstine, Yiying Zhang, Zhongcong Xie
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93737-0

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