Association between handgrip strength and vascular function in patients with hypertension
Background: Increased handgrip strength has been associated with lower cardiovascular and non-cardiovascular mortality in different populations. In patients with hypertension, arterial stiffness relates to cardiovascular mortality. However, whether muscle strength is associated with arterial stiffne...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-10-01
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| Series: | Clinical and Experimental Hypertension |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641963.2018.1539096 |
| _version_ | 1797681337516163072 |
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| author | Dalton de Lima-Junior Breno Quintella Farah Antonio Henrique Germano-Soares Aluísio Andrade-Lima Gustavo Oliveira Silva Sergio Luiz Cahu Rodrigues Raphael Ritti-Dias |
| author_facet | Dalton de Lima-Junior Breno Quintella Farah Antonio Henrique Germano-Soares Aluísio Andrade-Lima Gustavo Oliveira Silva Sergio Luiz Cahu Rodrigues Raphael Ritti-Dias |
| author_sort | Dalton de Lima-Junior |
| collection | DOAJ |
| description | Background: Increased handgrip strength has been associated with lower cardiovascular and non-cardiovascular mortality in different populations. In patients with hypertension, arterial stiffness relates to cardiovascular mortality. However, whether muscle strength is associated with arterial stiffness in hypertensives is unknown. Thus, the objective of this study was to analyze the association between handgrip strength and arterial stiffness parameters in hypertensive patients. Methods: Seventy-two hypertensive patients completed all evaluations and were included in the analysis. The ambulatory arterial stiffness index (AASI) was obtained based on 24-h ambulatory blood pressure monitoring. Carotid-femoral pulse wave velocity (cfPWV), and reflected wave indicator (AIx and AIx@75) were estimated using applanation tonometry technique, whereas handgrip strength test was performed using a digital dynamometer. Crude and adjusted linear regression models were performed. Results: The crude analysis revealed a negative association between handgrip strength and AASI (b = −0.41, p = 0.002) and AIx (b = −0.49, p < 0.001), and AIx@75 (b = −0.54, p < 0.001) which remained significant after adjustments for age, sex, and body mass index, mean blood pressure, and heart rate only for AASI (b = −0.46, p = 0.028) and AIx@75 (b = −0.24, p- = 0.040). Handgrip strength was not associated with cfPWV (p > 0.05). Conclusion: Handgrip strength is negatively associated with AASI and AIx@75, but not with AIx and cfPWV in hypertensive patients. |
| first_indexed | 2024-03-11T23:43:25Z |
| format | Article |
| id | doaj.art-e2466a54740349109538273619a61108 |
| institution | Directory Open Access Journal |
| issn | 1064-1963 1525-6006 |
| language | English |
| last_indexed | 2024-03-11T23:43:25Z |
| publishDate | 2019-10-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Clinical and Experimental Hypertension |
| spelling | doaj.art-e2466a54740349109538273619a611082023-09-19T15:19:28ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062019-10-0141769269510.1080/10641963.2018.15390961539096Association between handgrip strength and vascular function in patients with hypertensionDalton de Lima-Junior0Breno Quintella Farah1Antonio Henrique Germano-Soares2Aluísio Andrade-Lima3Gustavo Oliveira Silva4Sergio Luiz Cahu Rodrigues5Raphael Ritti-Dias6Federal University of PernambucoRural Federal University of PernambucoUniversity of PernambucoFederal University of SergipeUniversity of PernambucoRural Federal University of PernambucoUNINOVEBackground: Increased handgrip strength has been associated with lower cardiovascular and non-cardiovascular mortality in different populations. In patients with hypertension, arterial stiffness relates to cardiovascular mortality. However, whether muscle strength is associated with arterial stiffness in hypertensives is unknown. Thus, the objective of this study was to analyze the association between handgrip strength and arterial stiffness parameters in hypertensive patients. Methods: Seventy-two hypertensive patients completed all evaluations and were included in the analysis. The ambulatory arterial stiffness index (AASI) was obtained based on 24-h ambulatory blood pressure monitoring. Carotid-femoral pulse wave velocity (cfPWV), and reflected wave indicator (AIx and AIx@75) were estimated using applanation tonometry technique, whereas handgrip strength test was performed using a digital dynamometer. Crude and adjusted linear regression models were performed. Results: The crude analysis revealed a negative association between handgrip strength and AASI (b = −0.41, p = 0.002) and AIx (b = −0.49, p < 0.001), and AIx@75 (b = −0.54, p < 0.001) which remained significant after adjustments for age, sex, and body mass index, mean blood pressure, and heart rate only for AASI (b = −0.46, p = 0.028) and AIx@75 (b = −0.24, p- = 0.040). Handgrip strength was not associated with cfPWV (p > 0.05). Conclusion: Handgrip strength is negatively associated with AASI and AIx@75, but not with AIx and cfPWV in hypertensive patients.http://dx.doi.org/10.1080/10641963.2018.1539096muscle strengthdynamometerpulse wave velocityaugmentation index |
| spellingShingle | Dalton de Lima-Junior Breno Quintella Farah Antonio Henrique Germano-Soares Aluísio Andrade-Lima Gustavo Oliveira Silva Sergio Luiz Cahu Rodrigues Raphael Ritti-Dias Association between handgrip strength and vascular function in patients with hypertension Clinical and Experimental Hypertension muscle strength dynamometer pulse wave velocity augmentation index |
| title | Association between handgrip strength and vascular function in patients with hypertension |
| title_full | Association between handgrip strength and vascular function in patients with hypertension |
| title_fullStr | Association between handgrip strength and vascular function in patients with hypertension |
| title_full_unstemmed | Association between handgrip strength and vascular function in patients with hypertension |
| title_short | Association between handgrip strength and vascular function in patients with hypertension |
| title_sort | association between handgrip strength and vascular function in patients with hypertension |
| topic | muscle strength dynamometer pulse wave velocity augmentation index |
| url | http://dx.doi.org/10.1080/10641963.2018.1539096 |
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