Determination of trace elements in ibuprofen drug products using microwave-assisted acid digestion and inductively coupled plasma-mass spectrometry

Determination of trace elements in ibuprofen drug products using microwave-assisted acid digestion and inductively coupled plasma-mass spectrometry

Trace elements are found in most drugs as a result of the drug formulation and drug production methods. An inductively coupled plasma-mass spectrometry method for the determination of 24 trace elements (Mg, Ti, V, Cr, Mn, Cu, Fe, Co, Ni, Zn, As, Se, Mo, Ru, Rh, Pd, Ag, Cd, Sb, Ba, Ir, Pt, Au, and Pb...

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Bibliographic Details
Main Authors: Else Holmfred, Abdulla Alrijjal, C. Page Chamberlain, Katharine Maher, Stefan Stürup
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Ibuprofen
Pharmaceuticals
Trace elemental impurities
Acid digestion
ICP-MS
Analytical chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023107742

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