Comparative Analysis of Whole Transcriptome Profiles in Septic Cardiomyopathy: Insights from CLP- and LPS-Induced Mouse Models

Comparative Analysis of Whole Transcriptome Profiles in Septic Cardiomyopathy: Insights from CLP- and LPS-Induced Mouse Models

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, with septic cardiomyopathy being a common and severe complication. Despite its significant clinical impact, the molecular mechanisms underlying sepsis-induced cardiomyopathy (SICM) remain incompletely...

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Bibliographic Details
Main Authors: Karim Ullah, Yan Li, Qiaoshan Lin, Kaichao Pan, Tu Nguyen, Solanki Aniruddhsingh, Qiaozhu Su, Willard Sharp, Rongxue Wu
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Genes
Subjects:
sepsis-induced cardiomyopathy
gene sequencing
whole transcriptome profiles
septic animal models
cecal ligation and puncture
lipopolysaccharide
Online Access:https://www.mdpi.com/2073-4425/14/7/1366

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