The mouse QTL map helps interpret human genome-wide association studies for HDL cholesterol[S]

The mouse QTL map helps interpret human genome-wide association studies for HDL cholesterol[S]

Genome-wide association (GWA) studies represent a powerful strategy for identifying susceptibility genes for complex diseases in human populations but results must be confirmed and replicated. Because of the close homology between mouse and human genomes, the mouse can be used to add evidence to gen...

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Bibliographic Details
Main Authors: Magalie S. Leduc, Malcolm Lyons, Katayoon Darvishi, Kenneth Walsh, Susan Sheehan, Sarah Amend, Allison Cox, Marju Orho-Melander, Sekar Kathiresan, Beverly Paigen, Ron Korstanje
Format: Article
Language:English
Published: Elsevier 2011-06-01
Series:Journal of Lipid Research
Subjects:
genomics
high density lipoprotein
comparative genomics
quantitative trait loci
mouse model
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313328

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