Recombinant-attenuated Salmonella enterica serovar Choleraesuis vector expressing the PlpE protein of Pasteurella multocida protects mice from lethal challenge

Recombinant-attenuated Salmonella enterica serovar Choleraesuis vector expressing the PlpE protein of Pasteurella multocida protects mice from lethal challenge

Abstract Background Bacterial surface proteins play key roles in pathogenicity and often contribute to microbial adhesion and invasion. Pasteurella lipoprotein E (PlpE), a Pasteurella multocida (P. multocida) surface protein, has recently been identified as a potential vaccine candidate. Live attenu...

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Bibliographic Details
Main Authors: Guodong Zhou, Jiashuo Tian, Yichen Tian, Qifeng Ma, Quan Li, Shifeng Wang, Huoying Shi
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Veterinary Research
Subjects:
Recombinant attenuated Salmonella vaccine
P. multocida
PlpE
Vaccine candidate
Immune responses
Online Access:https://doi.org/10.1186/s12917-023-03679-0

Internet

https://doi.org/10.1186/s12917-023-03679-0

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