Gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancy
Gestational trophoblastic disease (GTD) is a group of benign and malignant tumors that develop from placental tissue and includes hydatidiform moles and gestational trophoblastic neoplasia (GTN). Invasive molar disease and choriocarcinoma are rare forms of GTN and can arise from any pregnancy event....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-08-01
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| Series: | Gynecologic Oncology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S235257892100117X |
| _version_ | 1818728799052759040 |
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| author | C. Toal A.A. Garrett S. Kostadinov M. Boisen |
| author_facet | C. Toal A.A. Garrett S. Kostadinov M. Boisen |
| author_sort | C. Toal |
| collection | DOAJ |
| description | Gestational trophoblastic disease (GTD) is a group of benign and malignant tumors that develop from placental tissue and includes hydatidiform moles and gestational trophoblastic neoplasia (GTN). Invasive molar disease and choriocarcinoma are rare forms of GTN and can arise from any pregnancy event. An interstitial ectopic pregnancy occurs with implantation within the intramural portion of the fallopian tube covered by myometrium. We present two cases of an invasive mole with pathology consistent with choriocarcinoma in situ arising from an interstitial ectopic pregnancies. We review management strategies including a minimally invasive surgical approach. Additionally we present a review of the literature of gestational trophoblastic disease associated with interstitial ectopic pregnancies. |
| first_indexed | 2024-12-17T22:35:44Z |
| format | Article |
| id | doaj.art-e2563272bfbe45c48e0558d6ffbbee14 |
| institution | Directory Open Access Journal |
| issn | 2352-5789 |
| language | English |
| last_indexed | 2024-12-17T22:35:44Z |
| publishDate | 2021-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Gynecologic Oncology Reports |
| spelling | doaj.art-e2563272bfbe45c48e0558d6ffbbee142022-12-21T21:30:05ZengElsevierGynecologic Oncology Reports2352-57892021-08-0137100813Gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancyC. Toal0A.A. Garrett1S. Kostadinov2M. Boisen3Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of UPMC, Pittsburgh, PA, United States; Corresponding author at: Department of Obstetrics and Gynecology, 300 Halket St, Pittsburgh 15213, PA, United States.Department of Gynecologic Oncology, Magee-Womens Hospital of UPMC, Pittsburgh, PA, United StatesDepartment of Pathology, Magee-Womens Hospital of UPMC, Pittsburgh, PA, United StatesDepartment of Gynecologic Oncology, Magee-Womens Hospital of UPMC, Pittsburgh, PA, United StatesGestational trophoblastic disease (GTD) is a group of benign and malignant tumors that develop from placental tissue and includes hydatidiform moles and gestational trophoblastic neoplasia (GTN). Invasive molar disease and choriocarcinoma are rare forms of GTN and can arise from any pregnancy event. An interstitial ectopic pregnancy occurs with implantation within the intramural portion of the fallopian tube covered by myometrium. We present two cases of an invasive mole with pathology consistent with choriocarcinoma in situ arising from an interstitial ectopic pregnancies. We review management strategies including a minimally invasive surgical approach. Additionally we present a review of the literature of gestational trophoblastic disease associated with interstitial ectopic pregnancies.http://www.sciencedirect.com/science/article/pii/S235257892100117XGestational trophoblastic diseaseMinimally invasive gynecologic surgery |
| spellingShingle | C. Toal A.A. Garrett S. Kostadinov M. Boisen Gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancy Gynecologic Oncology Reports Gestational trophoblastic disease Minimally invasive gynecologic surgery |
| title | Gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancy |
| title_full | Gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancy |
| title_fullStr | Gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancy |
| title_full_unstemmed | Gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancy |
| title_short | Gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancy |
| title_sort | gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancy |
| topic | Gestational trophoblastic disease Minimally invasive gynecologic surgery |
| url | http://www.sciencedirect.com/science/article/pii/S235257892100117X |
| work_keys_str_mv | AT ctoal gestationaltrophoblasticneoplasiapresentingasaninterstitialectopicpregnancy AT aagarrett gestationaltrophoblasticneoplasiapresentingasaninterstitialectopicpregnancy AT skostadinov gestationaltrophoblasticneoplasiapresentingasaninterstitialectopicpregnancy AT mboisen gestationaltrophoblasticneoplasiapresentingasaninterstitialectopicpregnancy |