MUC1 gene overexpressed in breast cancer: structure and transcriptional activity of the MUC1 promoter and role of estrogen receptor alpha (ERα) in regulation of the MUC1 gene expression
<p>Abstract</p> <p>Background</p> <p>The MUC1 gene encodes a mucin glycoprotein(s) which is basally expressed in most epithelial cells. In breast adenocarcinoma and a variety of epithelial tumors its transcription is dramatically upregulated. Of particular relevance to...
Main Authors: | Wreschner Daniel H, Gorivodsky Marat, Aylon Yael, Barnea Itay, Zaretsky Joseph Z, Keydar Iafa |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2006-11-01
|
Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/5/1/57 |
Similar Items
-
Suppression of MUC1-Overexpressing Tumors by a Novel MUC1/CD3 Bispecific Antibody
by: Jun Fang, et al.
Published: (2023-07-01) -
Analysis of MUC1 gene in goat
by: E. Cauvin, et al.
Published: (2011-03-01) -
MUC1, MUC2, MUC4, MUC5AC, Cdx2: immunohistochemical characteristics in polyps and adenocarcinoma of distal colon
by: M. A. Shyshkin
Published: (2019-05-01) -
Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas
by: Onur Oral, et al.
Published: (2020-01-01) -
MUC1 and MUC16: critical for immune modulation in cancer therapeutics
by: Xinyi Chen, et al.
Published: (2024-02-01)