An Inkjet Printed Flexible Electrocorticography (ECoG) Microelectrode Array on a Thin Parylene-C Film
Electrocorticography (ECoG) is a conventional, invasive technique for recording brain signals from the cortical surface using an array of electrodes. In this study, we developed a highly flexible 22-channel ECoG microelectrode array on a thin Parylene film using novel fabrication techniques. Narrow...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8220/22/3/1277 |
| _version_ | 1797484574183260160 |
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| author | Yoontae Kim Stella Alimperti Paul Choi Moses Noh |
| author_facet | Yoontae Kim Stella Alimperti Paul Choi Moses Noh |
| author_sort | Yoontae Kim |
| collection | DOAJ |
| description | Electrocorticography (ECoG) is a conventional, invasive technique for recording brain signals from the cortical surface using an array of electrodes. In this study, we developed a highly flexible 22-channel ECoG microelectrode array on a thin Parylene film using novel fabrication techniques. Narrow (<40 µm) and thin (<500 nm) microelectrode patterns were first printed on PDMS, then the patterns were transferred onto Parylene films via vapor deposition and peeling. A custom-designed, 3D-printed connector was built and assembled with the Parylene-based flexible ECoG microelectrode array without soldering. The impedance of the assembled ECoG electrode array was measured in vitro by electrochemical impedance spectroscopy, and the result was consistent. In addition, we conducted in vivo studies by implanting the flexible ECoG sensor in a rat and successfully recording brain signals. |
| first_indexed | 2024-03-09T23:06:19Z |
| format | Article |
| id | doaj.art-e25dc6872812499e9869a830ba09fa2d |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-09T23:06:19Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-e25dc6872812499e9869a830ba09fa2d2023-11-23T17:53:23ZengMDPI AGSensors1424-82202022-02-01223127710.3390/s22031277An Inkjet Printed Flexible Electrocorticography (ECoG) Microelectrode Array on a Thin Parylene-C FilmYoontae Kim0Stella Alimperti1Paul Choi2Moses Noh3American Dental Association Science & Research Institute, Gaithersburg, MD 20899, USAAmerican Dental Association Science & Research Institute, Gaithersburg, MD 20899, USADepartment of Electrical and Computer Engineering, University of Texas Rio Grande Valley, Edinburg, TX 78539, USADepartment of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA 19104, USAElectrocorticography (ECoG) is a conventional, invasive technique for recording brain signals from the cortical surface using an array of electrodes. In this study, we developed a highly flexible 22-channel ECoG microelectrode array on a thin Parylene film using novel fabrication techniques. Narrow (<40 µm) and thin (<500 nm) microelectrode patterns were first printed on PDMS, then the patterns were transferred onto Parylene films via vapor deposition and peeling. A custom-designed, 3D-printed connector was built and assembled with the Parylene-based flexible ECoG microelectrode array without soldering. The impedance of the assembled ECoG electrode array was measured in vitro by electrochemical impedance spectroscopy, and the result was consistent. In addition, we conducted in vivo studies by implanting the flexible ECoG sensor in a rat and successfully recording brain signals.https://www.mdpi.com/1424-8220/22/3/1277inkjet printingECoG sensormicroelectrode arrayParylene-Cflexible substrateneural probe |
| spellingShingle | Yoontae Kim Stella Alimperti Paul Choi Moses Noh An Inkjet Printed Flexible Electrocorticography (ECoG) Microelectrode Array on a Thin Parylene-C Film Sensors inkjet printing ECoG sensor microelectrode array Parylene-C flexible substrate neural probe |
| title | An Inkjet Printed Flexible Electrocorticography (ECoG) Microelectrode Array on a Thin Parylene-C Film |
| title_full | An Inkjet Printed Flexible Electrocorticography (ECoG) Microelectrode Array on a Thin Parylene-C Film |
| title_fullStr | An Inkjet Printed Flexible Electrocorticography (ECoG) Microelectrode Array on a Thin Parylene-C Film |
| title_full_unstemmed | An Inkjet Printed Flexible Electrocorticography (ECoG) Microelectrode Array on a Thin Parylene-C Film |
| title_short | An Inkjet Printed Flexible Electrocorticography (ECoG) Microelectrode Array on a Thin Parylene-C Film |
| title_sort | inkjet printed flexible electrocorticography ecog microelectrode array on a thin parylene c film |
| topic | inkjet printing ECoG sensor microelectrode array Parylene-C flexible substrate neural probe |
| url | https://www.mdpi.com/1424-8220/22/3/1277 |
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