A Comparative Study of Fractional CO2 Laser versus Intradermal Injection of Autologous Platelet Rich Plasma in Melasma
Introduction: Melasma is a common acquired hyperpigmentation disorder of the face involving the cheeks, forehead, and commonly the upper lips. This condition is more common in women. The objective of this study was to compare the efficacy of fractional CO2 laser and intradermal platelet rich plasma...
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| Format: | Article |
| Language: | English |
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Sonali Sharma on behalf of Rajasthan University of Health Sciences
2023-09-01
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| Series: | RUHS Journal of Health Sciences |
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| Online Access: | https://ruhsjhs.in/articleDetails.php?artid=TVRRNA== |
| _version_ | 1797681058233188352 |
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| author | Deepak Suganchand Bohara , Ankit Mehra , Rajkumar Kothiwala , Ashok Meherda , Leela Ram Rawat , Jitendra Kumar Garg |
| author_facet | Deepak Suganchand Bohara , Ankit Mehra , Rajkumar Kothiwala , Ashok Meherda , Leela Ram Rawat , Jitendra Kumar Garg |
| author_sort | Deepak Suganchand Bohara , Ankit Mehra , Rajkumar Kothiwala , Ashok Meherda , Leela Ram Rawat , Jitendra Kumar Garg |
| collection | DOAJ |
| description | Introduction: Melasma is a common acquired hyperpigmentation disorder of the face involving the cheeks, forehead, and commonly the upper lips. This condition is more common in women. The objective of this study was to compare the efficacy of fractional CO2 laser and intradermal platelet rich plasma (PRP) in melasma and to note down any 10.37821/ruhsjhs.4.2.2019.90-94 effects of fractional CO and autologous PRP in a prospective long 2 term follow up study. Methodology: A total of 60 patients with melasma attending the OPD of the Department of Dermatology were recruited. Half of study participants were treated with fractional CO laser treatments while the other half 2 were treated with intradermal autologous PRP once every two weeks for eight weeks. MASI score, visual analogue scale, objective and subjective assessment were done immediately before each session and two weeks after treatment. Results: The CO laser treatment created more variability 2 in MASI score due to effective treatment, while the PRP showed very little variability due to ineffective or less effective treatment results. Conclusion: Fractional CO laser is less invasive and 2 more effective as compared to intradermal injection of PRPin melasma patient. |
| first_indexed | 2024-03-11T23:39:23Z |
| format | Article |
| id | doaj.art-e25ee1f6e52646509eb8dae807afea7b |
| institution | Directory Open Access Journal |
| issn | 2456-8309 2582-3590 |
| language | English |
| last_indexed | 2024-03-11T23:39:23Z |
| publishDate | 2023-09-01 |
| publisher | Sonali Sharma on behalf of Rajasthan University of Health Sciences |
| record_format | Article |
| series | RUHS Journal of Health Sciences |
| spelling | doaj.art-e25ee1f6e52646509eb8dae807afea7b2023-09-19T16:25:51ZengSonali Sharma on behalf of Rajasthan University of Health SciencesRUHS Journal of Health Sciences2456-83092582-35902023-09-01http://dx.doi.org/10.37821/ruhsjhs.4.2.2019.90-94A Comparative Study of Fractional CO2 Laser versus Intradermal Injection of Autologous Platelet Rich Plasma in MelasmaDeepak Suganchand Bohara , Ankit Mehra , Rajkumar Kothiwala , Ashok Meherda , Leela Ram Rawat , Jitendra Kumar Garg0Postgraduate Student, Senior Resident, Head and Professor, Senior Professor, Department of Dermatology, JLN Medical College and Associated Group of Hospitals, Ajmer, Rajasthan, IndiaIntroduction: Melasma is a common acquired hyperpigmentation disorder of the face involving the cheeks, forehead, and commonly the upper lips. This condition is more common in women. The objective of this study was to compare the efficacy of fractional CO2 laser and intradermal platelet rich plasma (PRP) in melasma and to note down any 10.37821/ruhsjhs.4.2.2019.90-94 effects of fractional CO and autologous PRP in a prospective long 2 term follow up study. Methodology: A total of 60 patients with melasma attending the OPD of the Department of Dermatology were recruited. Half of study participants were treated with fractional CO laser treatments while the other half 2 were treated with intradermal autologous PRP once every two weeks for eight weeks. MASI score, visual analogue scale, objective and subjective assessment were done immediately before each session and two weeks after treatment. Results: The CO laser treatment created more variability 2 in MASI score due to effective treatment, while the PRP showed very little variability due to ineffective or less effective treatment results. Conclusion: Fractional CO laser is less invasive and 2 more effective as compared to intradermal injection of PRPin melasma patient.https://ruhsjhs.in/articleDetails.php?artid=TVRRNA==Not available |
| spellingShingle | Deepak Suganchand Bohara , Ankit Mehra , Rajkumar Kothiwala , Ashok Meherda , Leela Ram Rawat , Jitendra Kumar Garg A Comparative Study of Fractional CO2 Laser versus Intradermal Injection of Autologous Platelet Rich Plasma in Melasma RUHS Journal of Health Sciences Not available |
| title | A Comparative Study of Fractional CO2 Laser versus Intradermal Injection of Autologous Platelet Rich Plasma in Melasma |
| title_full | A Comparative Study of Fractional CO2 Laser versus Intradermal Injection of Autologous Platelet Rich Plasma in Melasma |
| title_fullStr | A Comparative Study of Fractional CO2 Laser versus Intradermal Injection of Autologous Platelet Rich Plasma in Melasma |
| title_full_unstemmed | A Comparative Study of Fractional CO2 Laser versus Intradermal Injection of Autologous Platelet Rich Plasma in Melasma |
| title_short | A Comparative Study of Fractional CO2 Laser versus Intradermal Injection of Autologous Platelet Rich Plasma in Melasma |
| title_sort | comparative study of fractional co2 laser versus intradermal injection of autologous platelet rich plasma in melasma |
| topic | Not available |
| url | https://ruhsjhs.in/articleDetails.php?artid=TVRRNA== |
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