Synthesis, spectral studies and antibacterial activity of Cu(II), Co(II) and Ni(II) complexes of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone
A new series of Cu(II), Co(II) and Ni(II) complexes with the 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone ligand, C21H22N4O (LH), were synthesized by the reaction of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, hydrazone with (3,5-dimethyl-1H-pyrazo...
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| Format: | Article |
| Language: | English |
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Serbian Chemical Society
2009-08-01
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| Series: | Journal of the Serbian Chemical Society |
| Subjects: | |
| Online Access: | http://www.shd.org.rs/JSCS/Vol74/No8/08_3888_4284.pdf |
| _version_ | 1818807615212224512 |
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| author | PAULMONY THARMARAJ DEIVASIGAMANI KODIMUNTHIRI CLARENCE D. SHEELA CHAPPANI S. SHANMUGA PRIYA |
| author_facet | PAULMONY THARMARAJ DEIVASIGAMANI KODIMUNTHIRI CLARENCE D. SHEELA CHAPPANI S. SHANMUGA PRIYA |
| author_sort | PAULMONY THARMARAJ |
| collection | DOAJ |
| description | A new series of Cu(II), Co(II) and Ni(II) complexes with the 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone ligand, C21H22N4O (LH), were synthesized by the reaction of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, hydrazone with (3,5-dimethyl-1H-pyrazol-1-yl)methanol and characterized. The nature of the bonding and geometry of the complexes were deduced from elemental analysis, IR, electronic and 1H-NMR spectroscopy, and magnetic susceptibility and conductivity measurements. The studies indicated square-planar, tetrahedral and octahedral geometry for the copper(II), cobalt(II) and nickel(II) complexes, respectively. The ESR spectra of the copper(II) complex in acetonitrile at 300 and 77 K were recorded and their salient features are reported. The electrochemical behavior of the copper (II) complex was studied by cyclic voltammetry. The antimicrobial activity of the ligand and its metal complexes were studied against the following strains of microorganism: Staphylococcus aureus, Salmonella enterica typhi, Escherichia coli and Bacillus subtilis by the well diffusion method. Metal complexes showed enhanced antimicrobial activity compared with that of the free ligand. |
| first_indexed | 2024-12-18T19:28:29Z |
| format | Article |
| id | doaj.art-e260d39556f5484485ecdbce3f955f9b |
| institution | Directory Open Access Journal |
| issn | 0352-5139 |
| language | English |
| last_indexed | 2024-12-18T19:28:29Z |
| publishDate | 2009-08-01 |
| publisher | Serbian Chemical Society |
| record_format | Article |
| series | Journal of the Serbian Chemical Society |
| spelling | doaj.art-e260d39556f5484485ecdbce3f955f9b2022-12-21T20:55:49ZengSerbian Chemical SocietyJournal of the Serbian Chemical Society0352-51392009-08-01748-9927938Synthesis, spectral studies and antibacterial activity of Cu(II), Co(II) and Ni(II) complexes of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazonePAULMONY THARMARAJDEIVASIGAMANI KODIMUNTHIRICLARENCE D. SHEELACHAPPANI S. SHANMUGA PRIYAA new series of Cu(II), Co(II) and Ni(II) complexes with the 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone ligand, C21H22N4O (LH), were synthesized by the reaction of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, hydrazone with (3,5-dimethyl-1H-pyrazol-1-yl)methanol and characterized. The nature of the bonding and geometry of the complexes were deduced from elemental analysis, IR, electronic and 1H-NMR spectroscopy, and magnetic susceptibility and conductivity measurements. The studies indicated square-planar, tetrahedral and octahedral geometry for the copper(II), cobalt(II) and nickel(II) complexes, respectively. The ESR spectra of the copper(II) complex in acetonitrile at 300 and 77 K were recorded and their salient features are reported. The electrochemical behavior of the copper (II) complex was studied by cyclic voltammetry. The antimicrobial activity of the ligand and its metal complexes were studied against the following strains of microorganism: Staphylococcus aureus, Salmonella enterica typhi, Escherichia coli and Bacillus subtilis by the well diffusion method. Metal complexes showed enhanced antimicrobial activity compared with that of the free ligand.http://www.shd.org.rs/JSCS/Vol74/No8/08_3888_4284.pdf35-dimethyl-1-(hydroxymethyl)pyrazole2’-hydroxychalconemetal complexespyrazoleCu(II)Co(II) and Ni(II) complexesantimicrobial activity. |
| spellingShingle | PAULMONY THARMARAJ DEIVASIGAMANI KODIMUNTHIRI CLARENCE D. SHEELA CHAPPANI S. SHANMUGA PRIYA Synthesis, spectral studies and antibacterial activity of Cu(II), Co(II) and Ni(II) complexes of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone Journal of the Serbian Chemical Society 3 5-dimethyl-1-(hydroxymethyl)pyrazole 2’-hydroxychalcone metal complexes pyrazole Cu(II) Co(II) and Ni(II) complexes antimicrobial activity. |
| title | Synthesis, spectral studies and antibacterial activity of Cu(II), Co(II) and Ni(II) complexes of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone |
| title_full | Synthesis, spectral studies and antibacterial activity of Cu(II), Co(II) and Ni(II) complexes of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone |
| title_fullStr | Synthesis, spectral studies and antibacterial activity of Cu(II), Co(II) and Ni(II) complexes of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone |
| title_full_unstemmed | Synthesis, spectral studies and antibacterial activity of Cu(II), Co(II) and Ni(II) complexes of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone |
| title_short | Synthesis, spectral studies and antibacterial activity of Cu(II), Co(II) and Ni(II) complexes of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]hydrazone |
| title_sort | synthesis spectral studies and antibacterial activity of cu ii co ii and ni ii complexes of 1 2 hydroxyphenyl 3 phenyl 2 propen 1 one n2 3 5 dimethyl 1h pyrazol 1 yl methyl hydrazone |
| topic | 3 5-dimethyl-1-(hydroxymethyl)pyrazole 2’-hydroxychalcone metal complexes pyrazole Cu(II) Co(II) and Ni(II) complexes antimicrobial activity. |
| url | http://www.shd.org.rs/JSCS/Vol74/No8/08_3888_4284.pdf |
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