Comparison of interferon gamma release assay and CXCL9 gene expression assay for the detection of Mycobacterium bovis infection in African lions (Panthera leo)

Comparison of interferon gamma release assay and CXCL9 gene expression assay for the detection of Mycobacterium bovis infection in African lions (Panthera leo)

Mycobacterium bovis (M. bovis) infection has been identified in both domestic and wild animals and may threaten the conservation of vulnerable species including African lions (Panthera leo). There is a need to develop accurate ante-mortem tools for detection of M. bovis infection in African big cat...

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Bibliographic Details
Main Authors: Rachiel Gumbo, Tashnica T. Sylvester, Sven D. C. Parsons, Peter E. Buss, Robin M. Warren, Paul D. van Helden, Michele A. Miller, Tanya J. Kerr
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
African lion
CXCL9
gene expression assay
IFN-γ
interferon gamma release assay
Mycobacterium bovis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.989209/full

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