Optical Glucose Sensor Using Pressure Sensitive Paint

A glucose sensor is used as an essential tool for diagnosing and treating diabetic patients and controlling processes during cell culture. Since the development of an electrochemical-based glucose sensor, an optical glucose sensor has been devised to overcome its shortcomings, but this also poses a...

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Main Author: Jongwon Park
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/21/13/4474
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author Jongwon Park
author_facet Jongwon Park
author_sort Jongwon Park
collection DOAJ
description A glucose sensor is used as an essential tool for diagnosing and treating diabetic patients and controlling processes during cell culture. Since the development of an electrochemical-based glucose sensor, an optical glucose sensor has been devised to overcome its shortcomings, but this also poses a problem because it requires a complicated manufacturing process. This study aimed to develop an optical glucose sensor film that could be fabricated with a simple process using commercial pressure sensitive paints. The sensor manufacturing technology developed in this work could simplify the complex production process of the existing electrochemical or optical glucose sensors. In addition, a photometric method for glucose concentration analysis was developed using the color image of the sensor. By developing this sensor and analysis technology, the basis for glucose measurement was established that enables two-dimensional, online, and continuous measurement. The proposed sensor showed good linearity at 0–4 mM glucose in an aqueous sample solution, its limit of detection was 0.37 mM, and the response time was 2 min.
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spelling doaj.art-e263b338ac534a6bb7e3d7f180e2db062023-11-22T02:19:27ZengMDPI AGSensors1424-82202021-06-012113447410.3390/s21134474Optical Glucose Sensor Using Pressure Sensitive PaintJongwon Park0Department of Biomedical Engineering, Kyungil University, Gyeongsan 38428, KoreaA glucose sensor is used as an essential tool for diagnosing and treating diabetic patients and controlling processes during cell culture. Since the development of an electrochemical-based glucose sensor, an optical glucose sensor has been devised to overcome its shortcomings, but this also poses a problem because it requires a complicated manufacturing process. This study aimed to develop an optical glucose sensor film that could be fabricated with a simple process using commercial pressure sensitive paints. The sensor manufacturing technology developed in this work could simplify the complex production process of the existing electrochemical or optical glucose sensors. In addition, a photometric method for glucose concentration analysis was developed using the color image of the sensor. By developing this sensor and analysis technology, the basis for glucose measurement was established that enables two-dimensional, online, and continuous measurement. The proposed sensor showed good linearity at 0–4 mM glucose in an aqueous sample solution, its limit of detection was 0.37 mM, and the response time was 2 min.https://www.mdpi.com/1424-8220/21/13/4474optical glucose sensoroptical oxygen sensorpressure sensitive paintphotometry
spellingShingle Jongwon Park
Optical Glucose Sensor Using Pressure Sensitive Paint
Sensors
optical glucose sensor
optical oxygen sensor
pressure sensitive paint
photometry
title Optical Glucose Sensor Using Pressure Sensitive Paint
title_full Optical Glucose Sensor Using Pressure Sensitive Paint
title_fullStr Optical Glucose Sensor Using Pressure Sensitive Paint
title_full_unstemmed Optical Glucose Sensor Using Pressure Sensitive Paint
title_short Optical Glucose Sensor Using Pressure Sensitive Paint
title_sort optical glucose sensor using pressure sensitive paint
topic optical glucose sensor
optical oxygen sensor
pressure sensitive paint
photometry
url https://www.mdpi.com/1424-8220/21/13/4474
work_keys_str_mv AT jongwonpark opticalglucosesensorusingpressuresensitivepaint