Peculiarities of Seroprovalence to SARS-CoV-2 in the Population of the Middle and Southern Urals in the Early Period of the COVID-19 Pandemic
Relevance. At the end of 2019, the world was confronted with a novel coronavirus (SARS-CoV-2), In January 2020, WHO declared an epidemic related to SARS-CoV-2, a health emergency of international importance, and in March characterized the spread of the world. diseases like a pandemic.Purpose of the...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Numikom LLC
2021-07-01
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| Series: | Эпидемиология и вакцинопрофилактика |
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| Online Access: | https://www.epidemvac.ru/jour/article/view/1283 |
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| author | A. Yu. Popova E. B. Ezhlova A. A. Melnikova V. S. Smirnov L. V. Lyalina D. N. Kozlovskikh S. V. Luchinina S. V. Romanov N. N. Valeullina O. V. Dikonskaya G. G. Chirkova O. L. Malykh A. V. Ponomareva I. V. Chistyakova A. S. Kilyachina A. I. Yurovskikh A. A. Kotova A. A. Totolian |
| author_facet | A. Yu. Popova E. B. Ezhlova A. A. Melnikova V. S. Smirnov L. V. Lyalina D. N. Kozlovskikh S. V. Luchinina S. V. Romanov N. N. Valeullina O. V. Dikonskaya G. G. Chirkova O. L. Malykh A. V. Ponomareva I. V. Chistyakova A. S. Kilyachina A. I. Yurovskikh A. A. Kotova A. A. Totolian |
| author_sort | A. Yu. Popova |
| collection | DOAJ |
| description | Relevance. At the end of 2019, the world was confronted with a novel coronavirus (SARS-CoV-2), In January 2020, WHO declared an epidemic related to SARS-CoV-2, a health emergency of international importance, and in March characterized the spread of the world. diseases like a pandemic.Purpose of the study. Conduct a comparative analysis of the seroprevalence of the population of the Sverdlovsk and Chelyabinsk regions – the largest administrative territorial entities of the Middle and Southern Urals – against the backdrop of the COVID-19 pandemic.Materials and methods. The work was carried out under the program of the first stage of assessing the seroprevalence of the population of the Russian Federation according to a unified methodology developed by Rospotrebnadzor of the Russian Federation with the participation of the Saint Petersburg Pasteur Institute. The selection of participants was carried out by the method of questioning and randomization. The presence of antibodies to the SARS-CoV-2 nucleocapsid was determined in blood serum by the enzyme immunoassay.Results. Comparative analysis of the results showed that the incidence rate of COVID-19 in the Chelyabinsk region was consistently lower, and the seroprevalence at the first stage of the study was statistically significantly higher (p <0/05) than in the Sverdlovsk region. It was found that the incidence in both regions had a direct correlation with population density (r = 0.59; p <0.05). There were no differences between the compared areas in terms of seroprevalence among convalescents, people who had contact with COVID-19 patients, and asymptomatic volunteers with a positive PCR test. When analyzing seroprevalent volunteers in both regions, it was shown that the number of asymptomatic individuals varied within 94.4 ± 1.2% – 95.0 ± 0.95%. These data indicate that the majority of volunteers tolerated COVID-19 asymptomatically.Conclusions. A comparative study showed a statistically significant predominance of seroprevalence among the population of the Chelyabinsk region. It was found that an increase in seroprevalence at the population level was accompanied by a decrease in morbidity. Shown is a direct relationship between population density and the incidence rate. More than 90% of seropositive individuals in the compared areas showed asymptomatic course of coronavirus infection. |
| first_indexed | 2024-04-10T02:50:29Z |
| format | Article |
| id | doaj.art-e265836438f647df944f209e362d08e8 |
| institution | Directory Open Access Journal |
| issn | 2073-3046 2619-0494 |
| language | Russian |
| last_indexed | 2024-04-10T02:50:29Z |
| publishDate | 2021-07-01 |
| publisher | Numikom LLC |
| record_format | Article |
| series | Эпидемиология и вакцинопрофилактика |
| spelling | doaj.art-e265836438f647df944f209e362d08e82023-03-13T07:43:18ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942021-07-0120381810.31631/2073-3046-2021-20-3-8-18744Peculiarities of Seroprovalence to SARS-CoV-2 in the Population of the Middle and Southern Urals in the Early Period of the COVID-19 PandemicA. Yu. Popova0E. B. Ezhlova1A. A. Melnikova2V. S. Smirnov3L. V. Lyalina4D. N. Kozlovskikh5S. V. Luchinina6S. V. Romanov7N. N. Valeullina8O. V. Dikonskaya9G. G. Chirkova10O. L. Malykh11A. V. Ponomareva12I. V. Chistyakova13A. S. Kilyachina14A. I. Yurovskikh15A. A. Kotova16A. A. Totolian17Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человекаФедеральная служба по надзору в сфере защиты прав потребителей и благополучия человекаФедеральная служба по надзору в сфере защиты прав потребителей и благополучия человекаФБУН «Санкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им. Пастера» РоспотребнадзораФБУН «Санкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им. Пастера» РоспотребнадзораУправление Роспотребнадзора по Свердловской областиУправление Роспотребнадзора по Челябинской обл.ФБУЗ «Центр гигиены и эпидемиологии в Свердловской областиФБУЗ «Центр гигиены и эпидемиологии в Челябинской областиУправление Роспотребнадзора по Свердловской областиФБУЗ «Центр гигиены и эпидемиологии в Челябинской областиУправление Роспотребнадзора по Свердловской областиУправление Роспотребнадзора по Свердловской областиФБУЗ «Центр гигиены и эпидемиологии в Свердловской областиФБУЗ «Центр гигиены и эпидемиологии в Свердловской областиФБУЗ «Центр гигиены и эпидемиологии в Свердловской областиФБУЗ «Центр гигиены и эпидемиологии в Свердловской областиФБУН «Санкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им. Пастера» РоспотребнадзораRelevance. At the end of 2019, the world was confronted with a novel coronavirus (SARS-CoV-2), In January 2020, WHO declared an epidemic related to SARS-CoV-2, a health emergency of international importance, and in March characterized the spread of the world. diseases like a pandemic.Purpose of the study. Conduct a comparative analysis of the seroprevalence of the population of the Sverdlovsk and Chelyabinsk regions – the largest administrative territorial entities of the Middle and Southern Urals – against the backdrop of the COVID-19 pandemic.Materials and methods. The work was carried out under the program of the first stage of assessing the seroprevalence of the population of the Russian Federation according to a unified methodology developed by Rospotrebnadzor of the Russian Federation with the participation of the Saint Petersburg Pasteur Institute. The selection of participants was carried out by the method of questioning and randomization. The presence of antibodies to the SARS-CoV-2 nucleocapsid was determined in blood serum by the enzyme immunoassay.Results. Comparative analysis of the results showed that the incidence rate of COVID-19 in the Chelyabinsk region was consistently lower, and the seroprevalence at the first stage of the study was statistically significantly higher (p <0/05) than in the Sverdlovsk region. It was found that the incidence in both regions had a direct correlation with population density (r = 0.59; p <0.05). There were no differences between the compared areas in terms of seroprevalence among convalescents, people who had contact with COVID-19 patients, and asymptomatic volunteers with a positive PCR test. When analyzing seroprevalent volunteers in both regions, it was shown that the number of asymptomatic individuals varied within 94.4 ± 1.2% – 95.0 ± 0.95%. These data indicate that the majority of volunteers tolerated COVID-19 asymptomatically.Conclusions. A comparative study showed a statistically significant predominance of seroprevalence among the population of the Chelyabinsk region. It was found that an increase in seroprevalence at the population level was accompanied by a decrease in morbidity. Shown is a direct relationship between population density and the incidence rate. More than 90% of seropositive individuals in the compared areas showed asymptomatic course of coronavirus infection.https://www.epidemvac.ru/jour/article/view/1283sars-cov-2covid-19серопревалентностьбессимптомное течениесвердловская областьчелябинская областьнаселениеплотность населениязаболеваемость |
| spellingShingle | A. Yu. Popova E. B. Ezhlova A. A. Melnikova V. S. Smirnov L. V. Lyalina D. N. Kozlovskikh S. V. Luchinina S. V. Romanov N. N. Valeullina O. V. Dikonskaya G. G. Chirkova O. L. Malykh A. V. Ponomareva I. V. Chistyakova A. S. Kilyachina A. I. Yurovskikh A. A. Kotova A. A. Totolian Peculiarities of Seroprovalence to SARS-CoV-2 in the Population of the Middle and Southern Urals in the Early Period of the COVID-19 Pandemic Эпидемиология и вакцинопрофилактика sars-cov-2 covid-19 серопревалентность бессимптомное течение свердловская область челябинская область население плотность населения заболеваемость |
| title | Peculiarities of Seroprovalence to SARS-CoV-2 in the Population of the Middle and Southern Urals in the Early Period of the COVID-19 Pandemic |
| title_full | Peculiarities of Seroprovalence to SARS-CoV-2 in the Population of the Middle and Southern Urals in the Early Period of the COVID-19 Pandemic |
| title_fullStr | Peculiarities of Seroprovalence to SARS-CoV-2 in the Population of the Middle and Southern Urals in the Early Period of the COVID-19 Pandemic |
| title_full_unstemmed | Peculiarities of Seroprovalence to SARS-CoV-2 in the Population of the Middle and Southern Urals in the Early Period of the COVID-19 Pandemic |
| title_short | Peculiarities of Seroprovalence to SARS-CoV-2 in the Population of the Middle and Southern Urals in the Early Period of the COVID-19 Pandemic |
| title_sort | peculiarities of seroprovalence to sars cov 2 in the population of the middle and southern urals in the early period of the covid 19 pandemic |
| topic | sars-cov-2 covid-19 серопревалентность бессимптомное течение свердловская область челябинская область население плотность населения заболеваемость |
| url | https://www.epidemvac.ru/jour/article/view/1283 |
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