Molecular Characterization of Complement Component 3 (C3) in the Pearl Oyster Pinctada fucata Improves Our Understanding of the Primitive Complement System in Bivalve

Molecular Characterization of Complement Component 3 (C3) in the Pearl Oyster Pinctada fucata Improves Our Understanding of the Primitive Complement System in Bivalve

As the central component in the complement system, complement component 3 (C3) plays essential roles in both the innate and adaptive immune responses. Here, a C3 gene (designated as pf-C3) was obtained from the pearl oyster Pinctada fucata by RT-PCR and rapid amplification of cDNA ends (RACE). The p...

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Bibliographic Details
Main Authors: Zhongliang Wang, Xueru Liang, Guiying Li, Bai Liufu, Kaiqi Lin, Jinfeng Li, Jing Wang, Bei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
Pinctada fucata
innate immunity
complement component 3
C3
Luciferase reporter assays
phagocytosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.652805/full

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