Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network.
Thyroid stimulating hormone (TSH) hormone levels are normally tightly regulated within an individual; thus, relatively small variations may indicate thyroid disease. Genome-wide association studies (GWAS) have identified variants in PDE8B and FOXE1 that are associated with TSH levels. However, prior...
Main Authors: | Jennifer R Malinowski, Joshua C Denny, Suzette J Bielinski, Melissa A Basford, Yuki Bradford, Peggy L Peissig, David Carrell, David R Crosslin, Jyotishman Pathak, Luke Rasmussen, Jennifer Pacheco, Abel Kho, Katherine M Newton, Rongling Li, Iftikhar J Kullo, Christopher G Chute, Rex L Chisholm, Gail P Jarvik, Eric B Larson, Catherine A McCarty, Daniel R Masys, Dan M Roden, Mariza de Andrade, Marylyn D Ritchie, Dana C Crawford |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4249871?pdf=render |
Similar Items
-
The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies
by: McCarty Catherine A, et al.
Published: (2011-01-01) -
Applying semantic web technologies for phenome-wide scan using an electronic health record linked Biobank
by: Pathak Jyotishman, et al.
Published: (2012-12-01) -
Genome-wide study of resistant hypertension identified from electronic health records.
by: Logan Dumitrescu, et al.
Published: (2017-01-01) -
Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans.
by: Janina M Jeff, et al.
Published: (2014-01-01) -
eMERGEing progress in genomics---the first seven years
by: Dana C. Crawford, et al.
Published: (2014-06-01)